Clinical and pharmacological group: & nbsp

Other lipid-lowering agents

Included in the formulation
  • Revaite® Garlic Pearls
    capsules inwards 
  • АТХ:

    C.10.A.X   Other lipid-lowering drugs

    Pharmacodynamics:

    Means of plant origin. It has bactericidal, antiviral, fungicidal effects associated with phytoncides and glycoside with alliin. Garlic is effective against the causative agents of intestinal infections (dysentery, typhoid, pathogenic enterococci, Escherichia coli with altered enzymatic properties), staphylococci, alpha-hemolytic streptococci. Glycoside alliin under the influence of the enzyme allinase is converted into allicin, which has antimicrobial activity.

    Garlic is eubiotic, thanks to vitamins C, B, D, PP contributes to the normalization of functions of the automicroflora. It improves digestion, strengthens the formation and secretion of bile, lowers cholesterol and sugar in the blood, favorably affects metabolism, especially in diabetic patients, with obesity. Thanks to organic acids, vitamins, macro- and microelements (especially magnesium, potassium, selenium, zinc, manganese) stimulates blood formation, shows antihypoxic and angioprotective effects. Cardiotonic action in combination with the expansion of peripheral vessels and hypolipidemic action contributes tonormalization of the functions of the cardiovascular system, especially in elderly patients. The anthelminthic effect is manifested with ascariasis and enterobiosis.

    With external application, especially in fresh form, in addition to antimicrobial effects, antihistamine, analgesic, antipruritic, keratolytic and depigmenting effects are possible; stimulates hair growth.

    Pharmacokinetics:

    Insufficiently investigated in humans. Reduced activity of CYP2E1 by 39%.

    Indications:
    • IHD, angina pectoris, thrombophlebitis, migraine, transient cerebral circulatory disorders, after surgical interventions on the vascular bed (as part of combination therapy).
    • Chronic pyelonephritis (as part of combination therapy).
    • Fungal and parasitic diseases (as part of combination therapy).
    • Acute infectious and inflammatory diseases of the respiratory system, including rhinitis, tonsillitis, sinusitis, sinusitis, bronchitis, pneumonia.
    • Prevention and treatment of influenza and ARVI.
    • Chronic diseases of the digestive tract, dysbiosis, atonic constipation.
    • Neurocirculatory dystonia by hypertonic type, arterial hypertension, atherosclerosis.
    • Ascaridosis, enterobiosis.

    For external use: dermatitis, pyoderma, purulent wounds.

    X.J00-J06.J04   Acute laryngitis and tracheitis

    X.J00-J06.J03   Acute tonsillitis

    X.J00-J06.J02   Acute pharyngitis

    X.J00-J06.J01   Acute Sinusitis

    X.J00-J06.J00   Acute nasopharyngitis (runny nose)

    I.B65-B83.B77   Ascaridosis

    I.B65-B83.B80   Enterobiosis

    IX.I20-I25.I20   Angina pectoris [angina pectoris]

    IX.I10-I15.I10   Essential [primary] hypertension

    IX.I70-I79.I70   Atherosclerosis

    XIV.N10-N16.N11   Chronic tubulointerstitial nephritis

    XVIII.R50-R69.R53   Malaise and fatigue

    X.J10-J18.J15   Bacterial pneumonia, not elsewhere classified

    Contraindications:

    Hypersensitivity, acute and chronic kidney diseases, hypothyroidism, biliary tract dyskinesia hyperkinetic type, hepatitis, cholelithiasis, gastritis and peptic ulcer of the stomach and duodenum in the acute phase, pregnancy, lactation.

    Carefully:

    Age to 18 years (efficacy and safety not established).

    Pregnancy and lactation:

    Category of recommendations for FDA is not defined. Qualitative and well-controlled studies on humans and animals have not been conducted. There are indications of stimulation of labor. Do not apply.

    There is no information on the penetration into breast milk and the effect on the newborn. Do not use because of the development of colic in babies.

    Dosing and Administration:

    Inside for 1-2 capsules 3 times a day before or after meals, squeezed with a small amount of liquid.

    Side effects:

    Disorders from the gastrointestinal tract, lowering blood pressure, changing the smell of the skin, exhaled air.

    Perhaps: irritation of the kidney parenchyma, in high doses causes tachycardia, pain in the heart; when applied to the skin - hyperemia, burning, rash.

    Rarely: dyspepsia, allergic reactions.

    Overdose:

    Not described. Treatment is symptomatic.

    Interaction:

    Garlic strengthens the effect of antihypertensive drugs.

    Anticoagulants (heparin sodium, warfarin, acenocoumarol) when used together increase bleeding time and clotting time (do not apply together).

    Insulin soluble, hypoglycemic drugs (chlorpropamide, metformin, tolbutamide) when combined use increases hypoglycemia (dose adjustment is necessary).

    Herbs (Acidophilus) reduce the absorption of garlic in parallel reception (a mandatory break between meals is 3 hours).

    Special instructions:

    625 mg of the drug correspond to 2 cloves of garlic. During the application of garlic products, a change in the smell of the skin, exhaled air.

    Instructions
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