Depantol® (Depanthol®)

Composition Pharmacodynamics Indications Carefully Contraindications Dosing and Administration Side effects Form release / dosage
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Active substanceDexpanthenol + ChlorhexidineDexpanthenol + Chlorhexidine
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    • Dosage form: & nbspVaginal suppositories
    Composition:
    One suppository contains: active substances: dexpanthenol - 100 mg, chlorhexidine bigluconate - 16 mg (in the form of chlorhexidine bigluconate solution of 20% - 85.2 mg); auxiliary substances: macrogol mixture (macrogol 400 - 2%, macrogol 1500 - 98%) - 2814.8 mg.
    Description:
    Suppositories white or white with a grayish or yellowish hue of color, torpedo-shaped with a funnel-shaped depression. Marble is allowed.
    Pharmacotherapeutic group:Reparation of tissue stimulant
    ATX: & nbsp

    D.08.A.C.52   Chlorhexidine in combination with other drugs

    D.08.A.C   Biguanides and amidines

    Pharmacodynamics:

    Depantol® is a combined preparation for topical application, providing regenerative, antiseptic, metabolic action. Chlorhexidine, which is part of the drug, is active against gram-positive and gram-negative bacteria: Treponema pallidum, Chlamidia spp., Ureaplasma spp., Neisseria gonorrhoeae, Gardnerella vaginalis, Bacteroides fragilis, Escherichia coli, Staphylococcus spp., Streptococcus spp.; yeasts, dermatophytes, protozoa (Trichomonas vaginalis). Some strains are slightly sensitive to the drug Pseudomonas spp., Proteus spp., as well as resistant to acid-fast forms of bacteria, bacterial spores. Dexpanthenol, which is part of the drug, stimulates the regeneration of mucous membranes, normalizes cellular metabolism, accelerates mitosis and increases the strength of collagen fibers.

    Depantol® does not interfere with the functional activity of lactobacilli. It retains activity (albeit somewhat reduced) in the presence of blood, pus.

    Indications:

    Treatment of acute and chronic vaginitis; endo / exocervicitis, including those complicated by cervical ectopy.

    Treatment of true erosions of the cervix of a specific etiology (as part of complex therapy).

    The drug is used to improve the regeneration of the mucous membrane of the vagina and cervix after destructive treatment methods (diathermocoagulation, cryodestruction, laser erection), postoperative, postpartum periods.

    Contraindications:

    Hypersensitivity to the components of the drug.

    Pregnancy and lactation:

    Depantol® is approved for use during pregnancy and lactation.

    Dosing and Administration:

    Applied intravaginally.Before use, the suppository is freed from the contoured package.

    Introduce 1 suppository 2 times a day, for 7-10 days. If necessary, it is possible to extend the course of treatment to 20 days.

    Side effects:

    Possible allergic reactions, itching, burning, passing after the withdrawal of the drug.

    Interaction:Depantol® is not compatible with detergents containing an anionic group (saponins, sodium lauryl sulfate, sodium carboxymethylcellulose) and soaps if they are administered intravaginally.
    Form release / dosage:Suppositories vaginal 100 mg + 16 mg.
    Packaging:
    5 suppositories are placed in a contour mesh package. 1 or 2 contiguous cell packs, along with instructions for the use of the drug, are placed in a pack of cardboard.
    Storage conditions:
    In the dark place at a temperature of no higher than 20 ° C.
    Keep out of the reach of children.
    Shelf life:2 years. Do not use the product after the expiry date printed on the package.
    Terms of leave from pharmacies:Without recipe
    Registration number:LSR-003902/07
    Date of registration:19.11.2007 / 15.05.2015
    Expiration Date:Unlimited
    The owner of the registration certificate:NIZHFARM, JSC NIZHFARM, JSC Russia
    Manufacturer: & nbsp
    Information update date: & nbsp24.03.2017
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