Pantoderm plus - instructions for use, dose, side effects, contraindications

Active substanceDexpanthenol + ChlorhexidineDexpanthenol + Chlorhexidine

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Pantoderm plus

cream externally

AKRIKHIN HFK, JSC Russia

Dosage form: & nbspcream for external use

Composition:

100 g of cream contain:

active substances: dexpanthenol (D-panthenol) in terms of 100% substance 5,000 g; chlorhexidine bigluconate, substance-solution 20% in terms of chlorhexidine bigluconate 0.776 g;

Excipients: propylene glycol 9,000 g, squalane 3,000 g, paraffin liquid 14,000 g, paraffin soft white 5,000 g, dimethicone 1,000 g, cetostearyl alcohol [cetyl alcohol 60%, stearyl alcohol 40%] 6,700 g, macrogol cetostearate 2,300 g, pantolactone 0,500 g, water purified to 100 g.

Description:

The cream is white or almost white.

Pharmacotherapeutic group:tissue repair stimulant

ATX: & nbsp

D.08.A.C.52 Chlorhexidine in combination with other drugs

D.08.A.C Biguanides and amidines

Pharmacodynamics:

Pantoderm^® plus - combined preparation for topical application.

Dexpanthenol - vitamin B group, a derivative of pantothenic acid. Dexpanthenol is converted into an organism into pantothenic acid, which is an integral part of coenzyme A and participates in the processes of acetylation, carbohydrate and fat metabolism, in the synthesis of acetylcholine, corticosteroids,porphyrins; stimulates skin regeneration, normalizes cellular metabolism, accelerates mitosis and increases the strength of collagen fibers. It has a regenerating, metabolic and weak anti-inflammatory effect.

Chlorhexidine antimicrobial is an antiseptic. Effective against gram-positive and gram-negative bacteria, including Staphylococcus spp., Enterococcus spp., Pseudomonas aeruginosa, E. coli, Streptococcus spp., as well as yeast-like fungi and dermatophytes. Keeps activity in the presence of blood, pus, various secrets and organic substances.

The drug Pantoderm® Plus protects the wound surface from infections, suppresses the current infand accelerates healing.

Pharmacokinetics:

With topical application dexpanthenol quickly absorbed by the skin and converted to pantothenic acid, binds to plasma proteins (mainly with beta-globulin and albumin). Its concentration in the blood is 0.5-1 mg / l, in the blood serum - 100 μg / l. Pantothenic acid is not exposed in the body to metabolism (except for inclusion in coenzyme A), is excreted unchanged.

Chlorhexidine with local application is almost not absorbed.

Indications:

Treatment:

- wounds with the threat of infection, such as abrasions, scratches, cuts, bruises, cracks, burns;

- infected superficial skin lesions;

- for the treatment of postoperative wounds;

- with chronic wounds, for example, trophic ulcers of the lower leg, pressure sores;

- at cracks and an inflammation of nipples of mammary glands in the period of thoracal feeding.

Contraindications:

Hypersensitivity to the components of the drug.

For treatment or treatment in the area of the auricle.

In case of severe, deep or heavily soiled wounds (such injuries require medical intervention).

Pregnancy and lactation:

The drug Pantoderm® Plus can be used during pregnancy and during breastfeeding, avoiding applying it to large surfaces of the skin.

Dosing and Administration:

Outwardly. The drug is applied a thin layer on the previously cleaned wound surface or inflamed skin area once or several times a day.

Treatment of wounds can be carried out both in the open way and with the use of dressings.

Care for the mammary glands of nursing mothers: the cream is applied to the nipples after each feeding.

Side effects:

Allergic reactions are possible: hives, itching.

If any of the side effects indicated in the instructions are aggravated or any other side effects are noted, ne The instructions in this manual should be reported immediately to the doctor.

Overdose:

Data on overdose are not provided.

Interaction:

Chlorhexidine is incompatible with soap and other anionic substances.

As a precautionary measure for possible interaction (antagonism or inactivation) should not be used simultaneously with other antiseptics.

Special instructions:

Avoid contact with eyes. Avoid contact with mucous membranes.

The drug should not be used to treat and treat the auricle.

The drug is not used to treat severe, deep and heavily contaminated wounds (such injuries require medical intervention).

If the size of the wound for some time remains invariably large or the wound does not heal within 10-14 days, then in this case it is necessary to consult a doctor. This is also necessary in case the edges of the wound are highly hyperemic, the wound suddenly swells and there are severe pain or damage accompanied by a fever.

Effect on the ability to drive transp. cf. and fur:

The drug does not affect the ability to drive vehicles or engage in other potentially hazardous activities that require increased concentration and speed of psychomotor reactions.

Form release / dosage:

Cream for external use, 5% + 0.776%.

Packaging:

30 grams per aluminum tube.

Each tube together with the instruction for use is placed in a pack of cardboard.

Storage conditions:

At a temperature of no higher than 25 ° C. Do not freeze.

Keep out of the reach of children.

Shelf life:

2 years.

Do not use after the expiration date.

Terms of leave from pharmacies:Without recipe

Registration number:LP-003167

Date of registration:31.08.2015

Date of cancellation:2020-08-31

The owner of the registration certificate:AKRIKHIN HFK, JSC AKRIKHIN HFK, JSC Russia

Manufacturer: & nbsp

AKRIKHIN HFK, JSC Russia

Representation: & nbspAKRIKHIN OJSC AKRIKHIN OJSC Russia

Information update date: & nbsp09.01.2016

Illustrated instructions

Instructions

Pantoderm plus (Panthoderm plus)