The classification of adverse reactions is given by the frequency of development (number of reported cases / number of patients):
Very often (≥1 / 10) headaches and paresthesias.
Often (≥1 / 100 to <1/1000) cases of anaphylactoid reactions are described. They can be extremely heavy and even lethal, especially in patients with anamnestic indications of allergies.
These anaphylactoid reactions can occur regardless of the dose administered and are manifested by one or more of the following symptoms: angioedema, anaphylactic shock, collapse and cardiac arrest, lowering of arterial pressure, laryngeal edema, bronchospasm, laryngospasm, pulmonary edema, shortness of breath, stridor, cough, itching, rhinitis, sneezing, conjunctivitis, abdominal pain, chest pain, urticaria and rash. Some of these symptoms may be the first signs of a beginning anaphylactic shock. Perhaps the development of delayed reactions to the introduction of contrast.
Very rarely (<1/10000):
Change in general condition: malaise, severe sweating, chilliness, pale skin and fainting.
Reactions at the injection site: Very rare cases of contrast agent entry into surrounding tissues have been described.
From the skin and subcutaneous tissue: eczema, rash.
From the nervous system: generalized convulsions.
From the musculoskeletal system and connective tissue: muscle cramps, muscle weakness.