Preparations of eleutherococcus intensify the action of stimulants and analeptics (caffeine, camphor, phenamine, etc.) are physiological antagonists of drugs that depress the central nervous system (including neuroleptics, barbiturates, tranquilizers, and anticonvulsants).
With simultaneous use with digoxin, an increase in the concentration in the blood plasma of the latter is possible; with hypoglycemic drugs (including insulin) and anticoagulants may enhance the effect.