Ferretab® comp. (Ferretab® comp.)

Composition Pharmacodynamics Indications Carefully Contraindications Dosing and Administration Side effects Form release / dosage
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Active substanceIron fumarate + Folic acidIron fumarate + Folic acid
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  • Ferretab® comp.
    capsules inwards 
    VALEANT, LLC     Russia
    • Dosage form: & nbspCapsules of prolonged action.
    Composition:

    One capsule contains:

    3 mini-tablets with iron fumarate and 1 mini-tablet with folic acid:

    active ingredients: iron fumarate 163.56 mg (equivalent to 152.1 mg of dry matter, equivalent to 50 mg of iron), folic acid 0.54 mg (equivalent to 0.5 mg of dry matter);

    Excipients: mini-tablets iron fumarate: lactose monohydrate 3.42 mg, silicon dioxide colloid 0.6 mg, magnesium stearate 0.6 mg, methyl methacrylate and ethyl acrylate copolymer [2: 1] 4.66 mg; minibablet of folic acid: lactose monohydrate 24.21 mg, cellulose microcrystalline 24.25 mg, silicon dioxide colloid 0.5 mg, magnesium stearate 0.5 mg; capsule body: gelatin 36.4804 mg, azorubin dye 0,0742 mg, quinoline yellow dye 0.1484 mg, titanium dioxide 0.4960 mg;

    capsule cap: gelatin 24,3203 mg, azorubin dye 0,0498 mg, dye quinoline yellow 0.0996 mg, titanium dioxide 03303 mg.

    Description:

    Hard gelatin capsule (size # 2) in red, containing 3 round flat mini-tablets of reddish-brown color (iron fumarate) and 1 round flat minitablet of yellow color (folic acid). The presence of inclusions is allowed on the tablets.

    Pharmacotherapeutic group:Iron preparation + vitamin.
    ATX: & nbsp

    B.03.A.D.02   Iron fumarate in combination with folic acid

    Pharmacodynamics:

    FERRETAB COMP - a remedy for the treatment and prevention of iron deficiency.

    The preparation contains as active substances iron fumarate and folic acid. The iron fumarate - salt of iron, a microelement necessary for the synthesis of hemoglobin. When iron is used in the form of salts, its deficiency in the body is rapidly replenished, which leads to a gradual regression of clinical (weakness, fatigue, dizziness, tachycardia, tenderness and dry skin) and laboratory symptoms of anemia. Folic acid It is necessary for the normal maturation of megaloblasts and the formation of normoblasts. It stimulates erythropoiesis, participates in the synthesis of amino acids, nucleic acids, purines and pyrimidines, in the exchange of choline. When pregnancy protects the body from the effects of teratogenic factors. FERRETAB COMP helps maintain and restore normal levels of iron in the blood, and also prevents complications such as anemia, miscarriage, early childbirth and impaired mental development of the child that can occur with a lack of iron and folic acid in the body. The amount of assimilated iron varies between 5 and 35%.

    In the serum, iron binds to transferrin and is involved in the formation of hemoglobin, myoglobin, cytochrome oxidase, catalase and peroxidase, or is stored in the tissues of the body in the form of ferritin.

    Pharmacokinetics:

    Excretion of iron occurs with feces, urine and sweat. Folic acid absorbed mainly in the upper intestinal tract (duodenum) and 64% protein bound. Folic acid it is metabolized in the liver and is secreted mainly through the kidneys, and also partially with faeces.

    Indications:

    Treatment and prevention of iron deficiency conditions caused by pregnancy, impaired iron absorption from the gastrointestinal tract, prolonged bleeding, unbalanced and malnutrition.

    Contraindications:

    • Hypersensitivity to the components of the drug.
    • Diseases accompanied by the accumulation of iron in the body (aplastic and hemolytic anemia, thalassemia, hemosiderosis, hemochromatosis).
    • Disturbance in the assimilation of iron (sidero-sacrificial anemia, lead anemia, pernicious anemia (insufficiency of vitamin B12).
    • Anemia, which is not caused by a lack of iron or folic acid.

    Pregnancy and lactation:

    It is possible to use FERRETAB COMP during pregnancy and during breastfeeding in the presence of indications.

    Dosing and Administration:

    FERRETAB COMP are taken orally, 1 capsule per day on an empty stomach, with plenty of liquid. With a severe lack of iron or folic acid, you need to increase the dose to two or three capsules per day. Supportive treatment should be continued for at least 4 weeks after reaching a normal level of hemoglobin for the normalization of serum ferritin, reflecting iron stores in the body.

    Side effects:

    FERRETAB COMP is well tolerated by patients.

    In some cases, a temporary adverse effect on the gastrointestinal tract (feeling of filling and unpleasant sensations in the stomach, nausea, vomiting), allergic reactions, constipation is possible.

    Overdose:

    Symptoms - it is possible to intensify the manifestations of the described side effects. When suspected of overdose, a study should be made of the serum iron content and the level

    Interaction:

    With the simultaneous reception of FERRETAB Comp with antacids, iron absorption deteriorates. Simultaneous reception with ascorbic acid helps to improve the absorption of iron.It should avoid joint use with antibiotics of the tetracycline group in connection with a violation of iron absorption. Kolestyramine, phenytoin, phenobarbital, carbamazepine, sulfasalazine, hormonal contraceptives, folic acid antagonists, trimethoprim, triamterene, solid foods, bread, uncooked cereals, dairy products, eggs, tea, reduce iron absorption.

    Special instructions:

    Before starting therapy with iron, a serum iron serum ferritin (ie, documenting iron deficiency) should be examined.

    Therapy FERRETAB COMP should be performed prior to the normalization of the blood picture (8-12 weeks). At reception of a preparation there can be a dark staining of a feces, бензидиновая test - false positive.

    Form release / dosage:

    Capsules of prolonged action.

    10 capsules in PVC / Al blister.

    For 3 blisters together with instructions for use in a cardboard box.

    Packaging:

    10 capsules in PVC / Al blister.

    For 3 blisters together with instructions for use in a cardboard box.

    Storage conditions:

    In dry, dark place at a temperature of no higher than 25 ° C Keep out of the reach of children!

    Shelf life:

    3 years. Do not use after the expiration date.

    Terms of leave from pharmacies:On prescription
    Registration number:П N013723 / 01
    Date of registration:22.11.2011
    The owner of the registration certificate:VALEANT, LLC VALEANT, LLC Russia
    Manufacturer: & nbsp
    Representation: & nbspVALEANT LLC VALEANT LLC Russia
    Information update date: & nbsp13.09.2013
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