Included in the formulation
АТХ:C.05.B.A.53 Heparin in combination with other drugs
C.05.B.A Heparin-containing preparations for topical application
Pharmacodynamics:Combination agent for topical application.
Sodium Heparin
Anticoagulant direct action. By activating antithrombin III accelerates its anticoagulant effect. It blocks the synthesis of thrombin, reduces the aggregation of platelets. Reduces the activity of hyaluronidase. Prevents formation and promotes resorption of existing thrombi, improves local blood flow, has anti-inflammatory and anti-edematous effect.
Dexpanthenol
After absorption into the skin it is transformed into pantothenic acid - vitamin B5. Pantothenic acid is a component of coenzyme A, which takes part in metabolic processes, thereby improving the processes of regeneration and epithelization of damaged skin areas.
Troxerutin
Angioprotector from the group of bioflavonoids. It blocks the venodilating effect of acetylcholine, bradykinin and histamine.Reduces permeability and fragility of capillaries, has a weak antiaggregant effect. Improves trophism and reduces swelling of the tissue associated with venous insufficiency.
Pharmacokinetics:The drug for topical application, systemic action on the body does not.
Indications:It is used to treat injuries of soft tissues: sprains, dislocations, hematomas. Used for edematous pain syndrome due to venous insufficiency of the lower extremities, as well as to enhance the epithelialization of trophic ulcers.
IX.I80-I89.I80 Phlebitis and thrombophlebitis
IX.I80-I89.I83.2 Varicose veins of the lower extremities with ulcer and inflammation
IX.I80-I89.I83 Varicose veins
IX.I80-I89.I87.0 Postphlebitic syndrome
IX.I80-I89.I87.2 Venous insufficiency (chronic) (peripheral)
IX.I80-I89.I89 Other non-infectious diseases of lymphatic vessels and lymph nodes
XIX.T08-T14.T14.0 Superficial injury of unspecified area of the body
XIX.T08-T14.T14.3 Dislocation, stretching and overstrain of the capsular-ligamentous apparatus of the joint of the unspecified area of the body
Contraindications:Infected trophic ulcers, individual intolerance, children up to 3 years.
Carefully:Hypersensitivity.
Pregnancy and lactation:Recommendations for FDA - Category B. It is used during pregnancy and lactation.
Dosing and Administration:Outer in the form of a gel, applied to the affected areas 2-3 times a day for 2-3 weeks.
Side effects:
Allergic reactions.
Overdose:
Cases of overdose are not described.
Treatment is symptomatic.
Interaction:
Clinically significant interactions are not described.
Special instructions:
The agent is not intended for intravaginal and rectal administration, nor is it used in ophthalmology.