Combination drug for external use.
Hydrocortisone
By inhibition of phospholipase A activity2 and reducing the release of arachidonic acid from the phospholipids of cell membranes reduces the production of leukotrienes and prostaglandins. Due to this suppresses the development of inflammatory manifestations: pain, swelling, fever and redness in the area of inflammation. It inhibits the expression of the cyclooxygenase-2 gene, which also leads to inhibition of prostaglandin synthesis.
Reduces the main substance of the connective tissue, weakening the exudative and proliferative processes in the skin. Inhibits cellular kinins, which have proteolytic activity. Prevents the access of macrophages and T-sensitized lymphocytes to the foci of inflammation.
It has anti-inflammatory, anti-edematous and anti-allergic effect.
Chloramphenicol
Inhibits peptidyl transferase, as a result of which the protein in the stage of amino acid transfer to the ribosome stops in the microbial cell. It penetrates into cells of microorganisms and acts on microbes inside: chlamydia, rickettsia.Bacteriostatic acts against gram-positive: Staphylococcus spp., Streptococcus spp. and Gram-negative bacteria: Escherichia coli, Haemophilus influenzae, Neisseria gonorrhoeae, Neisseria meningitidis Salmonella spp., Serratia spp., Shigella spp., Klebsiella spp., Yersinia spp., Proteus spp., Rickettsia spp., and Spirochaetaceae and some large viruses.