Included in the formulation
АТХ:C.01.E.X Other combination drugs for the treatment of heart disease
Pharmacodynamics:Combined antioxidant drug containing interchangeable amino acids: glutamic, glycine and cysteine. Regulates metabolism, increases the concentration of glutathione inside the cell, stimulates the activity of glutathione-dependent enzymes involved in oxidation-reduction reactions and oxygen utilization in tissues.
It improves the contractility of the myocardium, increases physical efficiency, improves thinking, dynamics of nervous processes in the brain, memory, has anticonvulsant activity and anti-anxiety action. Reduces motor excitability, organizes behavior. Normalizes sleep, reduces the toxic effects of alcohol and other drugs that depress the central nervous system. Improves psychoemotional state in patients with chronic cardiac insufficiency, contributes to the restoration of working capacity after physical exertion.
Pharmacokinetics:After sublingual application, the maximum concentration in the blood plasma is reached after 5-10 minutes.
Metabolism in the liver.Penetrates through the blood-brain barrier. Elimination by the kidneys.
The half-life is 5 hours. Elimination by the kidneys.
Indications:It is used to treat the syndrome of autonomic dysfunction in children 12-18 years old. It is used in the complex therapy of chronic heart failure in children 12-18 years old and adults. It is used to prevent physical fatigue in sports for children aged 11-15.
VI.G90-G99.G90 Disorders of the autonomic nervous system
IX.I30-I52.I50 Heart failure
V.F40-F48.F45 Somatoform disorders
Contraindications:Children under 11 years of age, individual intolerance.
Carefully:Hypersensitivity.
Pregnancy and lactation:Recommendations for FDA - Category B. It is used with caution during pregnancy and lactation in cases where the intended benefit exceeds the risk to the fetus and newborn.
Dosing and Administration:For 1 (70/70/70 mg) tablet sublingually 3 times a day, regardless of meal time.
The highest daily dose: 210/210/210 mg (3 tablets).
The highest single dose: 70/70/70 mg (1 tablet).
Side effects:Allergic reactions.
Overdose:Cases of overdose are not described.
Treatment is symptomatic.
Interaction:Clinically significant interactions are not described.
Special instructions:The drug is compatible with β-adrenoblokatorami, ACE inhibitors, aldosterone antagonists, blockers of slow calcium channels and organic nitrates.