Clinical and pharmacological group: & nbsp

NSAIDs - Salicylic acid derivatives

Included in the formulation
  • Holisal®
    gel Stomat. 
    VALEANT, LLC     Russia
  • АТХ:

    A.01.A.D   Other preparations for topical use in diseases of the oral cavity

    A.01.A.D.11   Other preparations for the treatment of diseases of the oral cavity

    Pharmacodynamics:

    Salicylic acid

    Non-selectively suppresses COX1 and COX2, regulating the synthesis of prostaglandins. It indiscriminately suppresses synthetases of prostaglandins. Suppresses the production of anti-inflammatory cytokines. Has analgesic and anti-inflammatory effect.

    Cetalkonium chloride

    Antiseptic, is active against bacteria, viruses and fungi.

    Pharmacokinetics:

    The drug for topical application, no systemic effect.

    Indications:

    It is used to treat inflammatory diseases and injuries of the oral mucosa. Used for surgical interventions, with toothache associated with acute inflammatory process, for treatment of thrush.

    XI.K00-K14.K05   Gingivitis and periodontal disease

    XI.K00-K14.K12   Stomatitis and related lesions

    XI.K00-K14.K13.7   Other and unspecified lesions of the oral mucosa

    XXI.Z80-Z99.Z97.2   Presence of a denture device

    Contraindications:

    Age under 1 year, individual intolerance.

    Carefully:

    Hypersensitivity to salicylates.

    Pregnancy and lactation:

    Recommendations for FDA - Category C. It is used with caution during pregnancy and lactation in cases where the intended benefit exceeds the risk to the fetus and newborn.

    Dosing and Administration:

    Use in children

    Contraindicated up to 1 year.

    The gel column 0.5 cm long should be rubbed into the lesions of the oral mucosa.

    Adults

    Locally, 2-3 times a day for anesthesia: after meals and at bedtime.

    The highest daily dose: 2-3 cm gel.

    The highest single dose: a column of gel 1 cm long.

    Side effects:

    Local Reactions: burning sensation in the place of application.

    Allergic reactions.

    Overdose:

    Cases of overdose are not described.

    Treatment is symptomatic.

    Interaction:

    Clinically significant interactions are not described.

    Special instructions:

    After using the gel, do not eat or rinse your mouth for 30 minutes.

    Instructions
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