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Dosage form: & nbspextract liquid for oral administration
Composition:

To prepare 1000 ml of extract it is necessary:

Horse chestnut of ordinary seeds - 1000 g;

Ethyl alcohol 60% (ethanol) - a sufficient amount to obtain 1 liter of extract.

Description:

Transparent liquid is yellowish brown in color, with a specific odor. During storage, a precipitate may form.

Pharmacotherapeutic group:Vetotonizing agent of plant origin
ATX: & nbsp
  • Other drugs that reduce the permeability of capillaries
  • Pharmacodynamics:

    Extract liquid from the seeds of horse chestnut ordinary as active substances contains triterpene saponins, the main component is escin.

    The drug has a pronounced angioprotective, anti-inflammatory and analgesic effect.

    Pharmacological action of the drug is caused by a decrease in the concentration of lysosomal enzymes, as a result of which the decomposition of mucopolysaccharides in the capillary walls decreases, vascular permeability decreases, preventing the filtration of low molecular weight proteins, electrolytes and water into the intercellular space. In addition, the drug has moderate antioxidant, antihypoxic activity and diuretic properties.

    Indications:

    As a symptomatic agent in the complex treatment of varicose veins and chronic venous insufficiency 3-4 classes on the clinical International Classification of chronic diseases of the veins of the lower extremities (CEAP), accompanied by pain, a sense of heaviness and a feeling of tension in the lower extremities, night cramps of the calf muscles, edema of the legs .

    Contraindications:

    Hypersensitivity to the components of the drug, pregnancy, lactation, age under 18,

    Carefully:Functional diseases of the liver, kidneys, alcoholism, craniocerebral trauma, brain diseases, simultaneous reception of anticoagulants.
    Dosing and Administration:

    Inside.

    For 12-15 drops with a small amount of liquid 3 times a day for 30-40 minutes before meals.

    The course of treatment is 4 weeks.

    The expediency of conducting a second course is determined by the doctor.

    Side effects:

    Allergic reactions are possible (fever, skin rash, hives, angioedema, rarely anaphylactic shock), dyspepsia (nausea, heartburn).

    Overdose:

    When using the drug in doses exceeding the recommended, it is possible to increase the side effects.

    Treatment: symptomatic.

    Interaction:

    It is possible to increase the effect of indirect anticoagulants.

    Special instructions:

    In case of insufficient or unsatisfactory symptomatic effect during 4 weeks of treatment, the patient should be advised to consult a doctor regarding other possible causes of edema.

    If there is a sudden appearance of severe symptoms of venous insufficiency (especially on one leg) - swelling, skin discoloration, a feeling of tension and heat, pain, you should see a doctor to exclude thrombosis of the veins of the lower extremities.

    The absolute ethyl alcohol content in the maximum single dose of the drug is 0.15 g, in the maximum daily dose 0.47 g.

    Form release / dosage:Extract for oral administration is liquid.
    Packaging:

    For 40 ml, go to 50 ml bottles of orange glass with a screw mouth, sealed with plastic stoppers and screwed caps.

    Each vial with the instruction for use is placed in a cardboard box.

    Storage conditions:

    At a temperature of 8-25 ° C, in a place protected from light.

    Keep out of the reach of children.

    Shelf life:

    2 years.

    Do not use after the expiration date.

    Terms of leave from pharmacies:On prescription
    Registration number:LSR-000007/10
    Date of registration:11.01.2010
    Expiration Date:Unlimited
    The owner of the registration certificate:CAMELIA NPP, LLC CAMELIA NPP, LLC Russia
    Manufacturer: & nbsp
    Representation: & nbspCAMELIA NPP LLC CAMELIA NPP LLC Russia
    Information update date: & nbsp16.01.2018
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