Corilip (Corylip)

Composition Pharmacodynamics Indications Carefully Contraindications Dosing and Administration Side effects Form release / dosage
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Active substanceKokarboksilaza + Riboflavin + Tioctic acidKokarboksilaza + Riboflavin + Tioctic acid
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  • Corilip
    suppositories rect. 
    ALTFARM, LLC     Russia
  • Corilip-Neo
    suppositories rect. 
    ALTFARM, LLC     Russia
    • Dosage form: & nbsprectal suppositories
    Composition:

    For 1 suppository:

    Active substances:

    kokarboksilazy hydrochloride - 25 mg, riboflavin - 2 mg, lipoic acid (thioctic acid) - 12 mg;

    Excipients: fat solid (fatty acid glycerides) - 911 mg.

    Description:

    Suppositories of yellow color, torpedo-shaped with possible impregnations of orange-yellow color.

    Pharmacotherapeutic group:Metabolic means
    ATX: & nbsp

    A.11.E.X   B group vitamins in combination with other drugs

    Pharmacodynamics:

    Combined drug, the effect of which is determined by the effects of its constituent vitamins and coenzymes, as well as their synergistic effect.

    Co-carboxylase (coenzyme) catalyzes carboxylation and decarboxylation α-ketokislot, participates in the processes of carbohydrate metabolism. Through participation in the pentose cycle, indirectly regulates the synthesis of nucleic acids, proteins, lipids. Promotes correction of metabolic acidosis and cellular hypoxia, as well as other metabolic disorders (insufficiency of the liver, kidneys, cardiovascular system, chronic intoxication).

    Riboflavin (vitamin B2) as a coenzyme of flavinproteins participates in the regulation of oxidation-reduction reactions (in the processes of carbohydrate, protein and fat metabolism). It plays an important role in the synthesis of hemoglobin and in maintaining the normal visual function of the eye, the condition of the mucous membranes and skin.

    Thioctic acid is involved in the oxidative decarboxylation of pyruvic acid and other α-ketokislot, in the regulation of lipid and carbohydrate metabolism, plays an important role in the process of formation of energy in the body. Thioctic acid Has a hepatoprotective effect, improves the detoxification function of the liver, protects against the effects of exo- and endotoxins.

    Coripil improves tissue metabolism under various physiological and pathological conditions, requiring correction by cofactors and substrates.

    Indications:

    The drug is indicated for use with a preventive and curative purpose in complex therapy for various pathological conditions in children and adults, such as:

    - Chronic tissue hypoxia;

    - Decreased immunity;

    - Bacterial and viral infections, including acute intestinal infections;

    - Chronic somatic diseases;

    - Chronic intoxication;

    - Dysfunction (hypotrophy) in children.

    Children before entering the children's institution, before the vaccination.

    Adults and children with intense physical and mental stress, with stressful situations, conditions after severe illnesses.

    As a restorative prophylactic for adults and children during the epidemic of infectious diseases.

    As a metabolic remedy in women in preparation for pregnancy and in the development of feto-placental insufficiency during pregnancy.

    Contraindications:

    Children up to 1 year.

    Hypersensitivity reaction to the components of the drug.

    Inflammation or bleeding in the rectum (contraindication associated with the route of administration).

    Pregnancy and lactation:

    Possible use during pregnancy. It should be refrained from using during breastfeeding (there are no clinical data).

    Dosing and Administration:

    The drug is used rectally (injected into the rectum).

    Suppositories prescribe to children from 1 year to 6 years, 1 suppository per day; children from 6 to 14 years, 1-2 suppositories per day,children over 14 years and adults 2-3 suppositories per day.

    The duration of the course of treatment for bacterial and viral infections is 6-9 days. At other pathological conditions at children - 10 days, the general duration of treatment - 3 - 4 courses with an interval in 20 days (3-4 month).

    With intense physical and mental stress, with stressful situations, conditions after severe illnesses, before goingBefore the introduction of preventive vaccinations, during the epidemic of infectious diseases, the duration of the course is 10 days.

    In pregnancy, the duration of treatment is 10 days. The total duration of treatment is 4-5 courses at intervals of 20 days. Women preparing for pregnancy, to apply the drug for 3 to 6 months before pregnancy, courses for 10 days after 20 days.

    Side effects:

    Allergic reactions are possible - hives, itching, bronchospasm, dyspeptic phenomena.

    If side effects occur, discontinue use and consult a doctor.

    Overdose:Cases of overdose are not described.
    Interaction:

    Negative interaction was not observed. The drug can be used in complex therapy.

    Special instructions:Criteria for the duration of treatment along with the clinical status are the cytochemical indices of the activity of peripheral blood leukocyte enzymes (succinate dehydrogenase and glycerophosphate dehydrogenase).
    Effect on the ability to drive transp. cf. and fur:The drug does not affect the ability to drive vehicles and mechanisms.
    Form release / dosage:

    Suppositories rectal (25 mg + 2 mg + 12 mg).

    Packaging:For 5 suppositories in a contour cell box from a polyvinyl chloride film. Two contour packs together with instructions for use in a pack of cardboard.
    Storage conditions:

    In the dark place at a temperature of no higher than 20 ° C. Keep out of the reach of children.

    Shelf life:

    2 years. Do not use after the expiration date printed on the package.

    Terms of leave from pharmacies:On prescription
    Registration number:P N002545 / 01-2003
    Date of registration:18.07.2008 / 28.04.2012
    Expiration Date:Unlimited
    The owner of the registration certificate:ALTFARM, LLC ALTFARM, LLC Russia
    Manufacturer: & nbsp
    Information update date: & nbsp18.01.2018
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