Corilip-Neo (Corylip-Neo)

Composition Pharmacodynamics Indications Carefully Contraindications Dosing and Administration Side effects Form release / dosage
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Active substanceKokarboksilaza + Riboflavin + Tioctic acidKokarboksilaza + Riboflavin + Tioctic acid
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  • Corilip
    suppositories rect. 
    ALTFARM, LLC     Russia
  • Corilip-Neo
    suppositories rect. 
    ALTFARM, LLC     Russia
    • Dosage form: & nbsp

    Rectal suppositories

    Composition:

    Composition per 1 suppository:

    Active substances:

    cocarboxylase hydrochloride - 12.5 mg, riboflavin - 1.0 mg, lipoic acid (thioctic acid) - 6.0 mg;

    Excipients: fat solid (fatty acid glycerides) - 930.5 mg.

    Description:

    Suppositories of yellow color, torpedo-shaped with possible impregnations of orange-yellow color.

    Pharmacotherapeutic group:Metabolic means.
    ATX: & nbsp

    A.11.E.X   B group vitamins in combination with other drugs

    Pharmacodynamics:

    Combined drug, the effect of which is determined by the effects of its constituent vitamins and coenzymes, as well as their synergistic effect.

    Cocarboxylase (coenzyme) catalyzes the carboxylation and decarboxylation of a-keto acids, participates in the processes of carbohydrate metabolism. Through participation in the pentose cycle, indirectly regulates the synthesis of nucleic acids, proteins, lipids. Promotes correction of metabolic acidosis and cellular hypoxia, as well as other metabolic disorders (insufficiency of the liver, kidneys, cardiovascular system, chronic intoxication).

    Riboflavin (vitamin B2) as a coenzyme of flavinproteins participates in the regulation of oxidation-reduction reactions (in the processes of carbohydrate, protein and fat metabolism). It plays an important role in the synthesis of hemoglobin and in maintaining the normal visual function of the eye, the condition of the mucous membranes and skin.

    Thioctic acid is involved in the oxidative decarboxylation of pyruvic acid and other a-keto acids, in the regulation of lipid and carbohydrate metabolism, plays an important role in the process of energy production in the body. Thioctic acid Has a hepatoprotective effect, improves the detoxification function of the liver, protects against the effects of exo- and endotoxins.

    Coripil improves tissue metabolism under various physiological and pathological conditions, requiring correction by cofactors and substrates.

    Pharmacokinetics:
    Indications:

    The drug is indicated for use with a preventive and curative purpose in complex therapy for various pathological conditions in children, such as:

    - Chronic tissue hypoxia;

    - Decreased immunity;

    - Bacterial and viral infections, including acute intestinal infections;

    - Chronic somatic diseases;

    - Chronic intoxication;

    - Dysfunction (hypotrophy) in children.

    Contraindications:

    Hypersensitivity reaction to the components of the drug.

    Inflammation or bleeding in the rectum (contraindication associated with the route of administration).

    Carefully:not described
    Pregnancy and lactation:not described
    Dosing and Administration:

    The drug is used rectally. Having released from the package, insert the suppository into the anus after pre-emptying the intestine. Suppositories prescribe to children up to 1 year of 1 suppository per day. The duration of the course of treatment is 10 days. The total duration of treatment is 3-4 courses with an interval of 20 days (3-4 month).

    Side effects:

    Allergic reactions are possible - hives, itching, bronchospasm, dyspeptic phenomena.

    If side effects occur, discontinue use and consult a doctor.

    Overdose:Cases of overdose are not described.
    Interaction:

    Negative interaction was not observed. The drug can be used for complex therapy.

    Special instructions:

    Criteria for the duration of treatment along with the clinical status are the cytochemical indices of the activity of leukocyte enzymesperipheral blood (succinate dehydrogenase and glycerophosphate dehydrogenase).

    Special instructions:
    Effect on the ability to drive transp. cf. and fur:
    Form release / dosage:

    Suppositories rectal (12.5 mg + 1 mg + 6 mg).

    Packaging:For 5 suppositories in a contour cell box from a polyvinyl chloride film. Two contour packs together with instructions for use in a pack of cardboard.
    Storage conditions:

    In the dark place at a temperature of no higher than 20 ° C. Keep out of the reach of children.

    Shelf life:

    2 years. Do not use after the expiration date printed on the package.

    Terms of leave from pharmacies:On prescription
    Registration number:LP-000092
    Date of registration:17.12.2010
    The owner of the registration certificate:ALTFARM, LLC ALTFARM, LLC Russia
    Manufacturer: & nbsp
    Information update date: & nbsp17.12.2010
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