Classification of the incidence of adverse events (WHO):
very often -> 1/10
often from> 1/100 to <1/10
infrequently - from> 1/1000 to <1/100
rarely from> 1/10000 to <1/1000
very rarely - from <1/10000, including individual messages.
From the nervous system:
often: headache, dizziness; rarely: migraine, drowsiness;
very rarely: convulsions, change and loss of taste, paresthesia, dyskinesia, fainting, aggressiveness; agitation, confusion, depression, insomnia, dystonia, tremor, tick, hallucinations, confusion;
From the respiratory system:
often: pharyngitis, rhinitis;
From the digestive system:
often: dryness of the oral mucosa, nausea;
rarely: abdominal pain;
Very rarely: diarrhea, impaired liver function (increased activity of "liver" transaminases, alkaline phosphatase, gamma-glutamintransferase and bilirubin concentration);
From the side of the cardiovascular system:
very rarely: tachycardia;
From the urinary system:
very rarely: upset urination, enuresis;
From the sense organs:
very rarely: disruption of accommodation, blurred vision, nystagmus;
From the skin:
very rarely: itching, rash, hives;
Allergic reactions:
very rarely: anaphylactic shock, angioedema, hypersensitivity reactions;
Other:
often: weakness;
very rarely: weight gain, asthenia, general malaise, edema of the lower limbs;
Laboratory indicators: thrombocytopenia.