Lysates of bacteria [Staphylococcus aureus, Streptococcus pyogenes, Streptococcus viridans, Streptococcus pneumoniae, Klebsiella pneumoniae, Klebsiella ozaenae, Haemophilus influenzae B, Neisseria catarrhalis] (Bacteriolysates [Staphylococcus aureus, Streptococcus pyogenes, Streptococcus viridans, Streptococcus pneumoniae, Klebsiella pneumoniae, Klebsiella ozaenae, Haemophilus influenzae B, Neisseria catarrhalis])

Clinical and pharmacological group: & nbsp

Other immunomodulators

Included in the formulation
  • Ismigen®
    pills n / az. 
    NIZHFARM, JSC     Russia
  • АТХ:

    L.03.A.X   Other immunostimulants

    Pharmacodynamics:

    Combined immunostimulating drug of bacterial origin for sublingual (sublingual) administration. It is a multivalent antigenic complex, which includes lysates of bacteria - the most common pathogens of respiratory infections. Lysates, which are part of the drug, are obtained by mechanical action. Like other immunostimulants of bacterial origin of the second generation, the drug has a nonspecific immunostimulating and specific vaccinating action.

    Stimulates both the local cellular and humoral immune response, and the systemic immune response. Activates phagocytosis, increases the content of lysozyme in saliva, helps increase the number of immunocompetent cells. Increases the functional and metabolic activity of macrophages (including alveolar) and polymorphonuclear leukocytes. As a result of treatment with the drug, the frequency, severity and duration of acute infections of the respiratory tract are reduced; there is relief and leveling of symptoms such as fever, cough, shortness of breath,decreases the need for antibacterial and anti-inflammatory therapy; in patients with chronic diseases of the respiratory tract, the drug also prevents exacerbations.

    Pharmacokinetics:

    Not studied.

    Indications:

    - Acute and subacute infections of the upper and lower respiratory tract: bronchitis, tonsillitis, pharyngitis, laryngitis, rhinitis, sinusitis, otitis media, including complications after the flu (treatment as part of combination therapy);

    - recurrent infections of the upper and lower respiratory tract, chronic bronchitis (prevention of exacerbations).

    VIII.H65-H75.H66   Purulent and unspecified otitis media

    X.J00-J06.J00   Acute nasopharyngitis (runny nose)

    X.J00-J06.J01   Acute Sinusitis

    X.J00-J06.J02   Acute pharyngitis

    X.J00-J06.J03   Acute tonsillitis

    X.J00-J06.J04   Acute laryngitis and tracheitis

    X.J20-J22.J20   Acute bronchitis

    X.J40-J47.J42   Chronic bronchitis, unspecified

    Contraindications:

    - hypersensitivity to the active and / or auxiliary components of the drug;

    - Pregnancy;

    - lactation;

    - Children's age up to 3 years.

    Carefully:No data.
    Pregnancy and lactation:

    Contraindicated use during pregnancy and lactation.

    FDA recommendations are not defined.

    Dosing and Administration:

    Acute and subacute infections of the upper and lower respiratory tract: 1 tablet a day until the symptoms disappear (at least 10 days).

    Recurrent infections of the upper and lower respiratory tract, prevention of exacerbations of chronic respiratory diseases: 1 tablet per day for 10 days. The preventive course includes three cycles of 10 days with 20-day intervals between them.

    Preventive course should be conducted no more than 1-2 times a year.

    Side effects:

    From the skin: very rarely - hives, impetiginous dermatitis, folliculitis.

    Other: very rarely - inflammation of the salivary gland, acute laryngitis, rhinitis.

    Overdose:

    No clinical symptoms of an overdose were noted. No reports of intoxication due to drug overdose.

    Interaction:

    The drug can be used concomitantly with other drugs intended for the treatment of acute and chronic respiratory diseases.

    The features of interaction with other drugs have not been described to date.

    Special instructions:

    Children between the ages of three and six years during the intake each day, until the tablets are completely dissolved in the oral cavity, should be under the supervision of adults. Does not affect the ability to drive vehicles and control mechanisms.

    Instructions
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