Intravenously in a dose: 50-70 mg / kg to the weakened patient, physically strong - 70-120 mg / kg, at a speed of 1-2 ml / min, dissolved in 50-100 ml of 5-40% glucose solution. The duration of the infusion is 10-20 minutes. This method of administration of an anesthesiologist can be used in cases where the drug is administered to a patient in the ward. After 5-7 minutes from the beginning of the drug, the patient falls asleep.It can also be administered for 1-2 minutes at a rate of 35-40 mg / kg in the maintenance mixture Sodium narcosis oxybugarate is additionally administered at a rate of 40 mg / kg. Anesthesia of sufficient depth for surgical intervention comes in 30-40 minutes from the beginning of the injection. This technique allows you to quickly (after the introduction of muscle relaxants) to intubate the trachea and begin surgical intervention with the additional administration of painkillers.
For introductory anesthesia in children sodium oxybutyrate prescribe intravenously drip in a dose of 100 mg / kg in 30-50 ml of 5% glucose solution for 5-10 minutes. Sleep occurs in 10-20 minutes. Duration of sleep from 1,5dos.
In heart surgery sodium oxybutyrate as an antihypoxic agent and a drug that prevents unwanted reactions to cooling is used at a dose of 100 mg / kg intravenously.
In hypoxic conditions, shock is used in a dose of 50-100 mg / kg. The maximum antihypoxic effect occurs 30-40 minutes after administration. The appearance on the electroencephalogram of slow delta waves interrupted by periods of isoelectric "silence" of the cortex is a criterion of sufficient, but not too deep (as opposed to other narcotic drugs) anesthesia.
With prolonged administration of the drug in large doses, potassium chloride should be administered to prevent possible hypokalemia (at a dose of 1/5 of the sodium oxybushrach dose).
For medical obstetric anesthesia, the drug is administered intravenously, slowly at a dose of 50-60 mg / kg in 20 ml of 40% glucose solution for 10-15 minutes. Sleep or superficial anesthesia lasts 1.5-3 hours. In case of transition to surgical delivery sodium oxybutyrate injected at a dose of 60-70 mg / kg and against this background, intubation anesthesia is performed with fractional administration of muscle relaxants.