Aminoglycoside antibiotic. It disrupts protein synthesis, suppressing the formation of a complex of transport and matrix RNA. In low concentrations bacteriostatic effect (due to violation of protein synthesis in microbial cells), in high concentrations - bactericidal (damages the cytoplasmic membranes of the microbial cell). Penetrates into the microbial cell, binds to specific receptor proteins on 30S subunit of ribosomes. Violates the formation of the complex transport and matrix RNA (30S subunit of the ribosome) and stops protein synthesis. It is active against a number of gram-positive and gram-negative aerobic microorganisms: Staphylococcus spp., Streptococcus spp.; moderately active in relation to aerobic bacteria - Corynebacterium diphtheriae, Listeria monocytogenes; enterobacteria - Escherichia coli, Salmonella spp.,.Shigella spp., Proteus spp., Enterobacter aerogenes, Klebsiella pneumonia, Vibrio cholerae; Mycobacterium tuberculosis, Haemophilus influenzae; He acts on Pseudomonas aeruginosa, anaerobic bacteria.
The resistance of microorganisms to neomycin develops slowly and to a small extent.
A drug Neomycin aerosol for external use inhibits the development of bacterial flora in the foci, inflammation of the skin. It also has drying and cooling effect.