Active substanceNicotineNicotine
Similar drugsTo uncover
  • Niquitin®
    patch cutaneous 
  • Niquitin® Mini
    pills n / az. 
  • Nicorette®
    spray locally 
  • Nicorette®
    patch externally 
  • Nicorette®
    lozenges
  • Nicorette®
    pills n / az. 
  • Nicorette
    solution d / inhal. 
  • Nicorette®
    lozenges
  • Nicorette®
    pills n / az. 
  • Nicorette®
    lozenges
  • Nicorette®
    solution d / inhal. 
  • Nicorette®
    lozenges
  • Nicorette®
    lozenges
  • Nicotinell®
    pills n / az. 
  • Nicotinell®
    patch cutaneous 
  • Dosage form: & nbspinhalation solution [absorbed]
    Composition:

    One cartridge (inhaler) contains:

    Active substance: nicotine - 10 mg

    Excipients: levomenthol - 1 mg, ethanol * - 133 mg, nitrogen - q.s., porous cylinder - 1 piece.

    * - evaporates in the production process.

    Description:Nicotine inhaler is a white or slightly colored porous cylinder in a sealed, transparent, plastic cartridge with an inscription "NICORETTE" and the specified number of the series.
    Pharmacotherapeutic group:a remedy for the treatment of nicotine addiction.
    ATX: & nbsp

    N.07.B.A   Drugs used in nicotine addiction

    N.07.B.A.01   Nicotine

    Pharmacodynamics:
    Indications:

    For the treatment of tobacco dependence by reducing the need for nicotine, the withdrawal of withdrawal symptoms arising with complete quitting from those who decided to quit smoking; facilitates temporary abstinence from smoking, and also helps to reduce the number of smoked cigarettes for those who can not or do not want to completely quit smoking.

    Contraindications:Hypersensitivity to nicotine or other components that make up the inhaler.
    Carefully:

    Patients with severe cardiovascular disease or hospitalized due to cardiovascular disease during the previous 4 weeks (peripheral artery occlusive disease, cerebrovascular disease, angina pectoris and heart failure in decompensation stage),with spasms of blood vessels, uncontrolled hypertension, rhythm disturbances, with severe / moderate liver diseases, severe kidney disease, gastric ulcer and duodenal ulcer in the acute stage, chronic pharyngeal diseases, asthma, COPD (chronic obstructive pulmonary disease).

    Nicotine, which enters the body both with substitution therapy with nicotine-containing drugs, and during smoking, causes adrenal release of catecholamines. Therefore, the "Nicoretgue" inhaler should be used with caution by patients with hyperthyroidism or pheochromocytoma.

    The Nicoretgue inhaler should not be used by persons under the age of 18 without a doctor's appointment. The experience of using the inhaler "Nicoretge" by teenagers under the age of 18 is absent.

    Pregnancy and lactation:

    Nicotine penetrates the placental barrier and affects the respiratory activity and blood circulation of the fetus. At the same time, the effect on blood circulation is dose-dependent. Smoking can cause serious harm to the fetus and the newborn, so smoking pregnant women women should recommend in full refuse from smoking without use substitution therapy with nicotine-containing drugs.

    Patients should be informed of the need to attempt to quit without nicotine replacement therapy. Smoking women during pregnancy and feeding should use the Nicorette inhaler only after consulting a doctor. The effect of using the Nicorette inhaler on children has not been fully studied. The use of nicotine-substituting therapy in pregnant women who can not refrain from smoking without such therapy significantly exceeds the risk of continuing smoking.

    Besides, nicotine is released with milk and can have a harmful effect on the newborn, even when taken in therapeutic doses.

    In order to reduce the negative effect of nicotine on the baby, the Nicorette inhaler should be used immediately after feeding.

    Dosing and Administration:
    The Nicorette inhaler should be used at the moment when there is an irresistible desire to smoke. The number of inhalations per day is selected individually, taking into account the degree of expression in a person of nicotine addiction. However, do not use more than 12 cartridges per day.The selected dose of inhalations can be used for 6-12 weeks, after which you should gradually stop using the Nicorette inhaler.
    When you quit smoking, the flow of nicotine into the body stops; at the same time you can develop various kinds of unpleasant sensations (headache, irritability, deterioration of sleep, etc.) - the so-called symptoms "cancellation". Using the Nicorette inhaler, you can prevent or at least minimize these symptoms. If inhaled through an inhaler, nicotine evaporates and is absorbed into the oral cavity. Absorption of nicotine occurs slowly, and at the same time high concentrations of nicotine can not be quickly created in the plasma, as occurs in tobacco smoking. In addition, unlike cigarettes, the Nicorette inhaler does not contain tar and does not deliver carbon monoxide into the body, as it does when smoking.

    Adult patients, including elderly patients

    One cartridge replaces 4 cigarettes. If you smoked 20 cigarettes a day, you should use 5 cartridges per day. Each cartridge can be used in about 4 doses, each take about 20 minutes. The recommended dose is 6-12 cartridges per day.

    The use of less than 5 cartridges can lead to the lack of effect of the therapy.

    Full cessation of smoking

    Use the inhaler for at least 3 months. Then you should start to gradually reduce the number of used cartridges. Even after giving up smoking, it is recommended to have a few spare cartridges in case of an irresistible desire to smoke.

    Reducing the number of cigarettes smoked The inhaler should be used when you want to smoke, gradually reducing the number of cigarettes smoked per day.

    If within 6 weeks you can not achieve a decrease in daily cigarette consumption, you should seek the help of a specialist.

    Try to completely abandon cigarettes should be taken as soon as you feel ready for it, but no later than 6 months after the start of therapy. If you could not make a serious attempt to quit smoking within 9 months after the start of therapy, you should contact a specialist.

    Typically, it is not recommended to use the inhaler for more than 6 months, but some people require longer therapy to not resume smoking or return to the previous level of tobacco use.

    Medical counseling and providing psychological support at the same time as Nicoretge inhaler therapy usually improve the effectiveness of therapy.

    In combination with a plaster (a transdermal therapeutic system with nicotine)

    The Nicorette inhaler can also be used in conjunction with a band-aid in those situations when, against the background of the use of a plaster, a person continues to periodically feel irresistible urge to Smoking, or if you could not quit smoking with using only an inhaler or only plaster. In combination with a plaster inhaler Nicorette allows you to quickly remove strong urges to smoking when it is necessary.

    Initial therapy:

    Treatment should be started with a 15 mg / 16 hour patch (Stage 1), applying it every morning to the undamaged,

    hair-free area of ​​skin shoulder or hip and taking off before bed, in combination

    with Nicorette inhaler 10 mg. Usually happens enough 4-5 cartridges per day. Do not use

    more than 12 cartridges per day. Initial therapy is carried out for 6-12 weeks, after which

    should gradually cancel the combined therapy.

    Abolition of combination therapy:

    Combine therapy can be canceled by two ways.

    Method 1: for the next 3-6 weeks it is necessary to switch from a plaster 15 mg / 16 hours (1

    stage) to the plaster 10 mg / 16 hours (stage 2), and then to the next 3-6 weeks on the plaster

    5 mg / 16 hours (stage 3) with the same amount inhalations, as with Initial therapy. Further

    gradually reduce the number of inhalations to complete cancellation within the time that

    it is necessary for a person depending on his needs, but no later than 12 months after the introduction of combined therapy. Method 2: is to completely remove the patch immediately after the end of the step Initial therapy. Then gradually reduce the number of inhalations until complete cancellation for the time that is necessary for a person depending on his needs, but no later than 12 months after the initiation of combined therapy. Recommended dose:

    Initial therapy

    Period

    time

    Patch

    Inhaler 10 mg

    The first 6 - 12 weeks

    1 plaster 15 mg / 16 hours (1 stage) daily

    By

    necessity. Recommended 4-5 cartridges per day

    Cancel - Method 1

    Next 3 - 6 weeks

    1 plaster 10 mg / 16 hours (2nd stage) daily

    Continue to use cartridges as needed

    The next 3-6 weeks

    1 plaster 5 mg / 16 hours (stage 3) daily

    Continue to use cartridges as needed

    Up to 12 months after the onset of combined therapy


    Gradual withdrawal from the use of an inhaler

    Cancel - method 2

    Up to 12 months after the onset of combined therapy


    Gradual withdrawal from the use of an inhaler

    Side effects:

    The use of the Nicorette inhaler can be accompanied by the development of the same side effects as with nicotine in other forms. The severity of side effects depends on the accepted dose of nicotine. Approximately 40% of cases develop minor local reactions, such as coughing and irritation of the oral and pharyngeal mucosa. Most of the side effects observed in patients develop within the first weeks after the start of treatment.

    - Irritation of the mucous membrane of the mouth and throat

    - Headache.

    - Cough.

    Frequently noted side effects (>1/100)

    1. Unpleasant sensations from the gastrointestinal tract, hiccough, nausea, vomiting.

    Nasal congestion Dizziness

    Less common (1/100 - 1/1000)

    Cardiopalmus.

    Rare (<1/1000)

    Paroxysmal atrial fibrillation.

    Such side effects as dizziness, headache, insomnia and anxiety can be manifestations of withdrawal symptoms caused by quitting. If you quit smoking, you can also increase the incidence of aphthous ulcers, the cause of which is not known.

    Overdose:

    In case of an overdose, the same symptoms are noted as with acute nicotine poisoning, namely: nausea, salivation, abdominal pain, diarrhea, sweating, headache, dizziness, hearing loss and marked general weakness. When high doses enter the body, hypotension, a weak and non-rhythmic pulse, respiratory depression, respiratory center paralysis, prostration, vascular collapse and generalized convulsions may be added to the above symptoms.

    Doses of nicotine, which are well tolerated during treatment by adult smokers, can cause symptoms of severe poisoning in young children, and even lead to death.

    Treatment

    You should immediately stop taking nicotine and begin symptomatic treatment. The intake of activated carbon prevents the absorption of nicotine in the gastrointestinal tract.

    Interaction:After quitting smoking, it is possible to increase the level in the blood plasma of certain medicines that are of important clinical importance and are characterized by a narrow "safety corridor", such as theophylline, tacrine and clozapine, and imipramine, olanzapine, clomipramine and fluvoxamine. In addition, there are some indications of a possible stimulating effect of smoking on the metabolism of flecainide and pentazokine.
    Special instructions:

    Patients with diabetes due to failure smoking may require a dose reduction insulin. There may be a development of transitional nicotine dependence, but the Nicotine does less harm than use tobacco.

    If the cartridge is swallowed, chewed, or sucked with nicotine (both used and not used), children are at risk of poisoning. Please note that at low temperatures the effectiveness of the Nicorette inhaler is reduced. Therefore, it is recommended to use the inhaler at a temperature above +15 ° C.

    Nicorette inhaler is effective An auxiliary tool, but remember that final success depends on the firmness of your decisions to stop smoking.

    If the medicine has become unusable or the expiration date has expired - do not dispose of it in the waste water or on the street! Place in a package and put in a garbage container. These measures will help to protect environment!

    Form release / dosage:Solution for inhalations, in one nicotine cartridge 10 mg.
    Packaging:(1) - inhalers (6) / complete with mouthpiece and plastic container / - packaging,
    (1) - inhalers (6) / complete with mouthpiece / - packings
    Storage conditions:

    At a temperature not higher than + 25 ° C, out of the reach of children.

    Shelf life:

    3 years.

    Do not use after the expiration date printed on the package. Note:

    The marking of the expiry date on the package (the period from the production date to the date specified in the item "go to") may be less than 3 years for 1 month.

    Terms of leave from pharmacies:Without recipe
    Registration number:П N012505 / 02
    Date of registration:24.11.2008
    The owner of the registration certificate:Johnson & Johnson, LLC Johnson & Johnson, LLC Russia
    Manufacturer: & nbsp
    Representation: & nbspJohnson & Johnson LLC Johnson & Johnson LLC Russia
    Information update date: & nbsphttp://grls.rosminzdrav.ru/Grls_View_v2.aspx?idReg=9795&t=
    Illustrated instructions
      Instructions
      Up