The incidence of side effects is distributed as follows: often - 1-10%; infrequently - 0.1-1%; rarely - 0.01-0.1%; very rarely - less than 0.001%, including individual cases.
From the central nervous system: infrequently - dizziness; rarely - fear, nervousness, "nightmarish" dreams; very rarely - headache, drowsiness, Reye's syndrome.
From the cardiovascular system: infrequently - lowering blood pressure; rarely - tachycardia, "hot flashes" of blood to the skin of the face and upper half of the trunk.
From the genitourinary system: infrequently - swelling; rarely - dysuria, hematuria, urinary retention; very rarely - renal failure, oliguria, interstitial nephritis.
From the digestive system: often - diarrhea, nausea, vomiting, increased activity of "liver" transaminases; infrequently - constipation, flatulence, gastritis; very rarely - abdominal pain, stomatitis, tarry stool, bleeding from the gastrointestinal tract, ulcer and / or perforation of the stomach or duodenum, hepatitis, incl. fulminant, jaundice, cholestasis.
From the skin: infrequently - itching, rash, increased sweating; rarely - erythema, dermatitis; very rarely - urticaria, angioedema, swelling of the face, multiforme exudative erythema, incl. Stevens-Johnson syndrome, toxic epidermal necrolysis (Lyell's syndrome).
From the hematopoiesis: rarely - anemia, eosinophilia; very rarely - thrombocytopenia, pancytopenia, purpura, hemorrhages, lengthening bleeding time. From the respiratory system: infrequently - shortness of breath; very rarely - exacerbation of previous bronchial asthma, bronchospasm.
From the sense organs: rarely - blurred vision.
Allergic reactions: rarely - hypersensitivity reactions; rarely - anaphylactoid reactions.
Other: infrequently hyperkalemia; rarely - general weakness; very rarely - hypothermia.