The frequency is classified according to the headings in accordance with the recommendations of the World Health Organization, depending on the occurrence of the event: Often (≥ 1/10), often (≥ 1/100, < 1/10), infrequently (≥ 1/1000, < 1/100), rarely (≥ 1/10000, < 1/1000), rarely (<1/10000), including individual messages.
Violations from the blood and lymphatic system:
rarely - Anemia, eosinophilia, hemorrhages;
rarely - thrombocytopenia, pancytopenia, purpura thrombocytopenic.
Immune system disorders:
rarely hypersensitivity reactions;
rarely - anaphylactoid reactions.
Disturbances from the skin and subcutaneous tissues:
infrequently - itching, skin rash, increased sweating;
rarely - dermatitis;
rarely - urticaria, angioedema, facial edema, polymorphic erythema, Stevens-Johnson syndrome, toxic epidermal necrolysis (Lyell's syndrome).
Impaired nervous system:
infrequently - dizziness;
rarely - headache, drowsiness, encephalopathy (Reye syndrome).
Disorders of the psyche:
rarely - a sense of fear, nervousness, nightmarish dreams.
Disorders from the side of the organ of vision:
rarely blurred vision.
rarely - impaired vision.
Hearing disorders and labyrinthine disturbances:
rarely - Vertigo.
Disorders from the cardiovascular system:
infrequently - Increased blood pressure;
rarely - tachycardia, lability of blood pressure, "tides" of blood to the skin of the face, a feeling of palpitations.
Disturbances from the respiratory system:
infrequently - dyspnea;
rarely - exacerbation of bronchial asthma, bronchospasm.
Disorders from the gastrointestinal tract:
often - diarrhea, nausea, vomiting;
infrequently - constipation, flatulence, gastritis, gastrointestinal bleeding, ulcer and / or perforation of the stomach or duodenum;
rarely - pain in the abdomen, dyspepsia, stomatitis, tarry stools.
Disorders from the liver and bile ducts:
often - increased activity of "hepatic" enzymes;
rarely - hepatitis, fulminant hepatitis (including lethal outcomes), jaundice, cholestasis.
Disorders from the kidneys and urinary tract:
rarely - dysuria, hematuria, urinary retention;
rarely - renal failure, oliguria, interstitial nephritis.
Violations from the water-electrolyte exchange:
rarely hyperkalemia.
Other:
infrequently - peripheral edema;
rarely - malaise, asthenia;
rarely hypothermia.