Below are the undesirable reactions listed by the frequency of their development, starting with the most frequent. The frequency of unwanted reactions is estimated as follows: very often (> 1/10); often (> 1/100, <1/10); sometimes (> 1/1000, <1/100); rarely (> 1/10000, <1/1000); very rarely (<1/10000), including individual messages:
Mental disorders:
Sometimes: confusion, psychomotor agitation, hallucinations;
Rarely: psychotic disorders, insomnia.
Rarely: increased libido, hypersexuality
From the side of the central nervous system:
Often: headache, drowsiness, dizziness;
Sometimes: movement disorders;
Rarely: drowsiness, paresthesia;
Rarely: increased drowsiness during the day, sudden falling asleep.
From the sense organs:
Rarely: impaired vision, blurred vision, tinnitus.
From the cardiovascular system:
Sometimes: arterial hypotension, orthostatic hypotension (very rarely leading to fainting);
Rarely: effusion to the pericardium, constrictive pericarditis, tachycardia, bradycardia, arrhythmia. Rarely: fibrosis of the heart valves, reversible paleness of the fingers and toes caused by hypothermia (especially in patients with Raynaud's syndrome in the anamnesis).
From the respiratory system, chest and mediastinum:
Often: nasal congestion;
Rarely: pleural effusion, pleural fibrosis, pleurisy, pulmonary fibrosis, dyspnea.
From the digestive system:
Often: nausea, constipation, vomiting;
Sometimes: dry mouth;
Rarely: diarrhea, abdominal pain, retroperitoneal fibrosis, gastrointestinal ulcers, gastrointestinal bleeding (black feces, blood in vomit masses).
From the skin and subcutaneous tissue:
Sometimes: allergic skin reactions, hair loss.
From the side of the musculoskeletal system and connective tissue:
Sometimes: cramps calf muscles.
Common violations and uyeakii at the place of introduction:
Sometimes: increased fatigue;
Rarely: peripheral edema;
Rarely: in the case of a sharp reversal of Parlodela development of a condition similar to a malignant neuroleptic syndrome.
In the application of Parlodel in high doses (as well as other dopamine agonists), reversible changes in sexual behavior, increased libido and hypersexuality, which disappeared after lowering the dose of the drug or stopping treatment, were rarely noted.
Application Parlodela for suppression of physiological lactation in the postpartum period in rare cases was accompanied by the development of arterial hypertension, myocardial infarction, seizures, stroke or mental disorders.