Included in the formulation
АТХ:L.03.A.X Other immunostimulants
Pharmacodynamics:Increased migration of T-lymphocytes and their interaction with B-lymphocytes, phagocytic activity of macrophages and production of factors of nonspecific resistance. Acceleration of tissue regeneration processes, stimulation of bone marrow hematopoiesis (including leukopoiesis).
It has immunomodulatory, immunostimulating and leukopoietic effects.
Pharmacokinetics:Not studied.
Indications:- complex therapy for infections occurring against the background of secondary immunodeficiency conditions (chronic nonspecific lung diseases, chronic recurrent viral and bacterial infections, poorly amenable to standard therapy, viral hepatitis and others);
- chronic purulent otitis;
- infectious allergic urticaria;
- chronic purulent diseases in children;
- secondary immunodeficiency conditions associated with aging, leukopenia, agranulocytosis;
- complex treatment of chronic inflammation of the lungs;
herpetic keratitis.
I.B15-B19.B19 Viral hepatitis, unspecified
III.D70-D77.D70 Agranulocytosis
III.D70-D77.D72 Other disorders of white blood cells
III.D80-D89.D84.9 Immunodeficiency, unspecified
VII.H15-H22.H19.1 * Keratitis due to herpes simplex virus, and keratoconjunctivitis (B00.5 +)
X.J10-J18.J18 Pneumonia without clarification of the pathogen
XII.L50-L54.L50.9 Hives, unspecified
Contraindications:- organic diseases of the myocardium with a violation of conductivity;
- individual intolerance;
- pregnancy and lactation.
Pregnancy and lactation:The category of FDA recommendations is not defined. The drug is not recommended for pregnancy and during breastfeeding.
Dosing and Administration:The drug is administered internally after meal. The daily dose is 1-2 g in 3-4 divided doses. Duration of treatment from 2 weeks up to 3 months or more.
Children under 1 year of 0,005-0,01 g per reception, from 2 to 5 years to 0,015-0,05 g, from 5 to 7 years to 0.05-0.1 g, from 8 to 14 years, 0, 2-0,3 g 3-4 times a day. People elderly and senile with reduced immunological activity of 1-1.5 grams in day within 2-3 weeks 2 times a year (in spring and autumn).
When leukopenia adults 0.1-0.2 g 4 times a day, the course - 10 days or more, depending on the course of the disease.
Side effects:CNS depression, bradycardia, dyspnea, allergic reactions (in rare cases).
Overdose:Not described, treatment is symptomatic.
Special instructions:In the therapy of herpetic keratitis, the intake is combined with the instillation of a 3% solution into the conjunctival sac of the eye 3 times a day.