From the nervous system and sensory organs: sleepiness (usually in the first days of treatment), lethargy, dizziness, fatigue, fatigue, headache, memory impairment, muscle weakness, ataxia, tremor, lubricated speech, weakness, paradoxical reactions in mentally ill, including psychomotor agitation, anxiety, ataxia.
From the hematopoiesis: leukopenia, neutropenia, agranulocytosis (chills, hyperthermia, sore throat, unusual fatigue or weakness), anemia, thrombocytopenia.
From the digestive system: dry mouth or salivation, heartburn, nausea, vomiting, decreased appetite, constipation, or diarrhea; a violation of liver function, increased activity of "liver" transaminases and alkaline phosphatase, jaundice.
From the genitourinary system: urinary incontinence, urinary retention, impaired renal function, weakened libido, dysmenorrhea.
Allergic reactions: skin rash, itching.
Influence on the fetus: teratogenicity, CNS depression, respiratory failure and suppression of sucking reflex in newborns whose mothers used the drug.
Other: addiction, drug dependence, reduction of blood pressure; rarely - depression of the respiratory center, impaired vision (diplopia), bulimia, weight loss, tachycardia, anterograde amnesia.
With a sharp reduction in dose or discontinuation arises withdrawal syndrome: irritability, headache, anxiety, excitement, agitation, a sense of fear, nervousness, sleep disturbance, dysphoria, spasm of smooth muscles of internal organs and skeletal muscles, depersonalization, increased sweating, depression, nausea, vomiting, tremor, perceptual disorders, including hyperacusis , paresthesia, photophobia, tachycardia, convulsions, hallucinations, rarely - acute psychosis).