Combined means.
Valerians of medicinal rhizomes with roots of tincture
In the rhizomes and roots of valerian contains essential oil with the main component - bornesteral ester with isovaleric acid, and free valerian acid, which has an antispasmodic effect.
The drug reduces the excitability of the central nervous system, has an antispasmodic effect. Mediately, through neuroregulatory mechanisms, regulates heart activity and has a direct effect on automatism and the conduction system of the heart. Has a moderate choleretic effect.
Lily of the valley herb tincture
Phytopreparation in the form of lily of the valley herb tincture in the concentration of 100 g / l. Providing blocking effect on the transport of sodium potassium ATPase, and then increases the content of sodium ions in cardiac myocytes, calcium channels open, calcium enters into the cell interior.An increase in the concentration of sodium accelerates the release of calcium from the sarcoplasmic reticulum and increases its content in the cell, thereby inhibiting the troponin complex, which inhibits the interaction of actin and myosin. The strength and speed of contraction of the cardiac muscle increases regardless of the preliminary stretching of the myocardium - the systole is shortened, becoming energetically economical. Increased myocardial contractility contributes to an increase in the shock volume of the blood.
Reduction of the end systolic and diastolic volumes of the heart together with an increase in myocardial tone reduces the size of the heart, reducing the need for myocardium in oxygen.
Carries out a negative chronotropic action, reduces the increased sympathetic activity, increasing the sensitivity of cardiopulmonary baroreceptors. Strengthening the activity of the vagus nerve, has an antiarrhythmic effect due to the elongation of the refractory period and a decrease in the rate of impulses through the atrioventricular node. The effect is improved by direct action on atrioventricular node and sympatholytic effects.