From the cardiovascular system: often excessive decrease in blood pressure and related symptoms, rarely - arrhythmia, angina, myocardial infarction, stroke.
From the urinary system: decreased kidney function, acute renal failure.
On the part of the respiratory system: often - a "dry" cough, difficulty breathing; rarely - bronchospasm, rhinorrhea.
From the digestive system: often - nausea, vomiting, abdominal pain, taste change, diarrhea or constipation, dry mouth, decreased appetite, cholus static jaundice, pancreatitis.
From the central nervous system: often - headache, asthenia, increased fatigue, dizziness, ringing in the ears, visual impairment, muscle cramps, paresthesia, rarely - decreased I, insomnia; very rarely confusion.
Allergic reactions: often - skin rash, itching; rarely - hives, angioedema; extremely rarely - multiforme exudative erythema.
Laboratory indicators: often - hypercreatininaemia, proteinuria, hyperkalemia, hyperuricemia; rarely (with prolonged use in high doses) - neutropenia, leukopenia, hypohemoglobinaemia, thrombocytopenia, a decrease in hematocrit; extremely rare - agranulocytosis, pancytopenia, increased activity of "hepatic" enzymes, hyperbilirubinemia, hemolytic anemia (against a background of deficiency of glucose-6-phosphate dehydrogenase).
Other: increased sweating, decreased potency.