Similar drugsTo uncover
Dosage form: & nbspointment for topical application
Composition:

Active substances:

hydrocortisone acetate

5.58 mg

framicetin sulfate (activity 670 mg / g)

10.00 mg

heparin sodium (activity 130 IU / mg)

100 ME

esculoside

10.00 mg

benzocaine (ethylaminobenzoate)

10.00 mg

butambene (butylaminobenzoate)

10.00 mg

Excipients: cholesterol, paraffin liquid, paraffin soft white, polysorbate 80, propylene glycol, macrogol (polyethylene glycol) 400, macrogol (polyethylene glycol) 4000, macrogol (polyethylene glycol) 1500.

Description:Ointment is almost white with a greenish-yellowish tinge.
Pharmacotherapeutic group:hemorrhoids treatment
ATX: & nbsp
  • Preparations for the treatment of hemorrhoids and anal fissures in combination
  • Pharmacodynamics:

    Hydrocortisone - Glucocorticosteroid, is an anti-inflammatory agent. Eliminates signs and symptoms of inflammation, such as: redness, swelling, pain, etc.

    Framicetin - is a broad-spectrum antibiotic for topical application from the aminoglycoside group. Framicetin is produced by some types of streptomycetes and was first isolated from Streptomyces lavendulae. In experiments in vitro shown, that ferricetin, like other aminoglycosides, affect protein synthesis by specific and irreversible inhibition of 30S subunits of ribosome bacteria,resulting in a mRNA read error, so ferricetin has bactericidal activity against a number of gram-negative rods (Escherichia coli, Klebsiella pneumoniae, Aerobacter species, Salmonella typhimmium, Salmonella paratyphi AT, Shigella species, Pasteurella multocida, Brucella species, Proteus vulgaris and others Proteus species, Pseudomonas aeruginosa and others Pseudomonas species, Serratia marcescens, Alcaligenes species and Bacillus subtilis), and Gram-positive cocci (Staphylococcus aureus, Staphylococcus epidermidis, Streptococcus pyogenes, Streptococcus faecalis, Streptococcus pneumoniae), and streptococci are less sensitive to framicetin. Framicetin does not affect pathogenic fungi, viruses, anaerobic flora. In clinical studies, the slow development of resistance of microorganisms to framicetin sulfate has been shown.

    Heparin sodium (sodium salt of heparin) is an anticoagulant. Prevents thrombotic complications of hemorrhoids.

    Aesculoside - a substance similar in its chemical structure to rutozide, reduces the increased fragility of capillaries.

    Benzocaine and butamben have a local anesthetic and antipruritic effect, reduce the spasm of the anal sphincter.

    The effect of the drug manifests itself in a few minutes after application.
    Indications:

    Internal and external acute and chronic hemorrhoids.

    Prevention of recurrence of internal and external hemorrhoids.

    Perianal eczema.

    Proctitis.

    Acute and chronic cracks in the anus.

    Operative removal of hemorrhoids (before and after surgery).

    Postpartum hemorrhoids.

    Contraindications:

    Hypersensitivity to the components of the drug.

    Tuberculosis, viral, fungal infection of the anorectal zone.

    Pregnancy and lactation.

    Children's age (due to the lack of clinical data on the use of the drug in children).

    Carefully:

    With arterial hypertension, heart failure.

    Dosing and Administration:

    A small amount of ointment is applied to the site of itching or pain localization in the morning and in the evening, and after each defecation.

    For a deeper introduction into the rectum, apply the applicator to the tube with ointment, insert it into the rectum, make sure that it is inserted deep enough, and then gently, pressing the tube from the lower end, insert the ointment into the rectum, gradually removing the applicator .

    Ointment can be used alone or in combination with rectal capsules Proctosedil® M.

    Proctosedil® is applied for a short time (not more than 7 days).

    Side effects:

    The feeling of discomfort in the rectum.

    Allergic reactions and other hypersensitivity reactions.

    Burning, dryness of the rectal mucosa.

    Accession of secondary infection.

    The risk of systemic side effects associated with the presence of hydrocortisone in the formulation (only when used in high doses and for a long time).

    Form release / dosage:

    Ointment for topical application.

    Packaging:

    10 grams of ointment in an aluminum tube.

    1 tuba together with instructions for use and a plastic nozzle (cannula dispenser) in a cardboard box.

    Storage conditions:

    Store at a temperature not exceeding 25 ° C.

    Keep out of the reach of children.

    Shelf life:

    2 years.

    Do not use after the expiration date.

    Terms of leave from pharmacies:Without recipe
    Registration number:П N011778 / 01
    Date of registration:11.12.2008 / 26.11.2015
    The owner of the registration certificate:Sanofi India LimitedSanofi India Limited India
    Manufacturer: & nbsp
    Representation: & nbspSanofi Aventis GroupSanofi Aventis Group
    Information update date: & nbsp15.02.2016
    Illustrated instructions
      Instructions
      Up