| Remestip® is intended for intravenous administration in the form of bolus injections or short-term infusion. |
Bleeding from the gastrointestinal tract (gastric and duodenal ulcers, varicose veins of the esophagus): 10 ml (1.0 mg) with an interval of 4-6 hours before the bleeding stops and the next 3-5 days.To prevent repeated bleeding, the drug is canceled only after a complete absence of bleeding within 24 - 48 hours. The drug can be used in the provision of first aid for suspected bleeding from the gastrointestinal tract.
Bleeding during surgery on the abdominal and pelvic organs: intravenously drip from 2 ml (0.2 mg) to 10 ml (1.0 mg) every 4 to 6 hours, depending on the activity of tissue endopeptidases.
Uterine bleeding (dysfunctional, with childbirth and abortion): 4 ml (0.4 mg) is added to 6 ml of 0.9% sodium chloride solution and injected para- and / or intracervical in 5-10 minutes before surgery. If necessary, the dose may be increased or decreased.
In juvenile uterine bleeding, the recommended dose is 5-20 μg / kg of the body weight of the patient.
Hepatorenal syndrome type 1: 10 ml (1 mg) 3-4 times a day. Treatment should continue until normal plasma creatinine levels (less than 130 μmol / L), on average, 10 days. If the creatinine level does not decrease by more than 30% within 3 days, further administration of the drug is impractical.