Retasol® (Retasol®)

Composition Pharmacodynamics Indications Carefully Contraindications Dosing and Administration Side effects Form release / dosage
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Active substanceIsotretinoinIsotretinoin
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    • Dosage form: & nbsp
    Solution for external use.

    Composition:
    Active substance: isotretinoin 0.25 mg
    Excipients: butylhydroxytoluene, butylhydroxyanisole, propylene glycol, ethanol (ethyl alcohol) 95% to 1 ml.
    Description:Transparent oily liquid from light yellow to yellow with a weak specific smell of ethanol.
    Pharmacotherapeutic group:A remedy for acne.
    ATX: & nbsp

    D.10.B.A.01   Isotretinoin

    Pharmacodynamics:Isotretinoin is one of the biologically active forms of vitamin A. It inhibits the terminal differentiation of sebocytes, the hyperproliferation of the epithelium of excretory ducts of the sebaceous glands, normalizes the composition of their secretions and facilitates its evacuation. Due to this, the production of sebum decreases, its isolation is facilitated, the composition is normalized, the inflammatory reaction around the glands is reduced.The solution has anti-seborrheic, anti-inflammatory, keratolytic action; strengthens the regeneration processes in the skin.
    Indications:In adults and adolescents older than 11 years, papulo-pustular and comedonal forms of acne vulgaris, rosacea (with a small amount of rashes), perioral dermatitis, indistinctly expressed seborrheic dermatitis. After the abolition of retinoids, applied either internally or rectally, it is possible to use the preparation Retasol® in order to maintain the achieved clinical effect.
    Contraindications:Increased individual sensitivity to the components of the drug. Contraindicated during pregnancy, breastfeeding and women planning a pregnancy.
    Carefully:Use with caution in chronic liver, kidney, chronic pancreatitis, decompensation of cardiac activity.
    Pregnancy and lactation:Contraindicated during pregnancy, breastfeeding and women planning a pregnancy.
    Dosing and Administration:The solution is applied with a cotton swab to the previously cleaned skin (after washing or rubbing with a tonic that does not contain alcohol) 2 times a day. Duration of treatment is 4-12 weeks.Repeated treatment is possible after consultation with a doctor.
    Side effects:
    In the first week of treatment, there may be a reaction of exacerbation - the appearance of new rashes, itching, swelling, redness and flaking of the skin. With a pronounced reaction, it is recommended to stop the treatment for a few days before it subsides. In some cases there is an intolerance of the drug - in the first or second day of application there are spotty-papular rashes, itching and puffiness. In such cases, you should cancel the drug and consult a doctor.

    Overdose:With long-term use, overdose phenomena are possible: redness and flaking of the skin at the site of application, cheilitis. The overdosage phenomena quickly pass after discontinuing the drug and applying local glucocorticosteroids.
    Interaction:The solution should not be given to patients receiving other preparations from the group of reginoids to reduce the risk of hypervitaminosis A. The effect of the solution is weakened with the simultaneous administration of antibiotics of the tetracycline group, as well as with topical application of glucocorticosteroids.
    Special instructions:It is not recommended to apply the solution to the skin around the eyes, as well as with severe acute inflammation. Do not apply to mucous membranes. During treatment, avoid exposure to sunlight, use sunscreens if necessary, preventive and therapeutic use of ultraviolet rays and visits to the solarium are not recommended.
    Effect on the ability to drive transp. cf. and fur:The drug does not affect the ability to drive and perform work that requires increased concentration.
    Form release / dosage:Solution for external use 0,025%.
    Packaging:Solution for external use 0,025% for 10, 15, 20, 30 and 50 ml in bottles of orange glass. Each bottle, along with instructions for medical use, is placed in a pack of cardboard.
    Storage conditions:In the dark place at a temperature of no higher than 22 ° C, not accessible to children.
    Shelf life:2 years. Do not use after expiry date.
    Terms of leave from pharmacies:Without recipe
    Registration number:P N001836 / 01
    Date of registration:06.10.2008
    The owner of the registration certificate:RETYNOIDS FNPP, CJSC RETYNOIDS FNPP, CJSC Russia
    Manufacturer: & nbsp
    Information update date: & nbsp21.09.2015
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