Serious skin reactions: Very rarely acute generalized exanthematous pustulosis (OGEP). Acute condition with development of pustular rashes.It is characterized by fever and diffuse erythema, accompanied by burning and itching. There may be swelling of the face, hands and mucous membranes; Stevens-Johnson syndrome (SSD) (malignant exudative erythema). Heavy form of erythema multiforme, in which there are bubbles on the mucous membrane of the mouth, throat, eyes, genitals, other areas of the skin and mucous membranes. Toxic epidermal necrolysis (TEN, Lyell's syndrome). Syndrome is the result of extensive apoptosis of keratinocytes, which leads to the detachment of large areas of skin in places dermoepidermalnogo connection. The affected skin looks like scalded boiling water.
If you notice one of the side effects described above, stop taking the medication and consult a doctor immediately! Allergic reactions: skin rash, itching, hives, angioedema.
From the nervous system. dizziness, falling asleep, increased excitability.
From the cardiovascular system: increased blood pressure, tachycardia.
On the part of the digestive system: nausea, vomiting, pain in the epigastric region, dryness of the oral mucosa, hepatotoxic effect.
From the sense organs: mydriasis, paresis of accommodation, increased intraocular pressure.
From the hemopoiesis: anemia, thrombocytopenia, agranulocytosis, hemolytic anemia, aplastic anemia, methemoglobinemia, pancytopenia.
From the urinary system: urinary retention, nephrotoxicity (papillary necrosis).
Other: bronchospasm.