Salicylic acid + Zinc oxide (Acidum salicylicum + Zinci oxydum)

Pharmacodynamics Pharmacokinetics Indications Carefully Contraindications Dosing and Administration Side effects
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Clinical and pharmacological group: & nbsp

Antiseptics and disinfectants

Included in the formulation
  • Galmanin
    powder externally 
    TULA PHARMACEUTICAL FACTORY, LTD.     Russia
  • Galmanin
    powder externally 
    IVANOVSKAYA Pharmaceutical Factory, OAO     Russia
  • Salicylic-zinc paste
    paste externally 
    SAMARAHEDPROM, JSC     Russia
  • Salicylic-zinc paste
    paste externally 
    TVERSKAYA PHARMACEUTICAL FACTORY, OJSC     Russia
  • Salicylic-zinc paste
    paste externally 
    MOSCOW PHARMACEUTICAL FACTORY, CJSC     Russia
  • Salicylic-zinc paste
    paste externally 
    SYNTHESIS, OJSC     Russia
  • Salicylic-zinc paste
    paste externally 
    YAROSLAVSK PHARMACEUTICAL FACTORY, CJSC     Russia
  • Salicylic-zinc paste
    paste externally 
    TULA PHARMACEUTICAL FACTORY, LTD.     Russia
    • АТХ:

    D.08.A.X   Other antiseptics and disinfectants

    Pharmacodynamics:

    Anti-inflammatory action salicylic acid is due to inhibition of COX-2 activity, which leads to a decrease in the production of inflammatory mediators - prostaglandins Pg D2, E2 and I2.

    Drying effect zinc oxide is due to the formation of albumins and denaturation of proteins. When applied to the affected surface of the skin reduces the severity of exudative processes, eliminates local manifestations of inflammation and irritation; has an adsorbing effect, forms a protective coating on the skin, which reduces the effect of irritants on it.

    Pharmacokinetics:

    Absorption from the skin surface is insignificant; association with plasma proteins; excretion mainly by the kidneys in the form of inactive metabolites.

    Indications:

    Subacute eczema of various etiology, hyperhidrosis of the feet.

    ICD-10

    XII.L20-L30.L30.0   Coin-like eczema

    XII.L20-L30   Dermatitis and eczema

    XII.L80-L99.L98.1   Artificial [artificially] dermatitis

    XII.L60-L75.L71.0   Perioral dermatitis

    XII.L20-L30.L25.9   Unspecified contact dermatitis, cause not specified

    XII.L20-L30.L25.8   Unspecified contact dermatitis due to other substances

    XII.L20-L30.L25.5   Unspecified contact dermatitis due to plants other than food

    XII.L20-L30.L25.4   Unspecified contact dermatitis due to food when exposed to skin

    XII.L20-L30.L25.3   Unspecified contact dermatitis due to other chemicals

    XII.L20-L30.L25.2   Unspecified contact dermatitis due to dyes

    XII.L20-L30.L25.1   Unspecified contact dermatitis due to medications in contact with skin

    XII.L20-L30.L25.0   Unspecified contact dermatitis due to cosmetics

    XII.L20-L30.L25   Contact dermatitis, unspecified

    XII.L20-L30.L24.9   Simple irritant contact dermatitis, cause not specified

    XII.L20-L30.L24.8   Simple irritant contact dermatitis due to other substances

    XII.L20-L30.L24.7   Simple irritant contact dermatitis caused by plants other than food

    XII.L20-L30.L24.6   A simple irritant contact dermatitis caused by food products when they come into contact with the skin

    XII.L20-L30.L24.5   Simple irritant contact dermatitis due to other chemicals

    XII.L20-L30.L24.4   A simple irritant contact dermatitis caused by drugs when they come into contact with the skin

    XII.L20-L30.L24.3   Simple irritant contact dermatitis caused by cosmetic means

    XII.L20-L30.L24.2   Simple irritant contact dermatitis due to solvents

    XII.L20-L30.L24.1   Simple irritant contact dermatitis due to oils and lubricants

    XII.L20-L30.L24   Simple irritant contact dermatitis

    XVIII.R50-R69.R61.9   Hyperhidrosis, unspecified

    XVIII.R50-R69.R61.0   Localized hyperhidrosis

    XVIII.R50-R69.R61   Hyperhidrosis

    Contraindications:

    Hypersensitivity, pregnancy, breast-feeding, age to 12 years.

    Carefully:

    Birthmarks, hairy warts, warts in the genital area or face, childhood, pregnancy, skin diseases, accompanied by inflammation, wetness.

    Pregnancy and lactation:

    Action category for the fetus by FDA - not determined (N). Do not apply.

    Dosing and Administration:

    Outwardly on the affected skin.

    Side effects:

    Allergic reactions; at long application and drawing on extensive surfaces salicylic acid has a resorptive effect.

    Overdose:

    Not described.

    Interaction:

    Clinically significant interactions are not described.

    Special instructions:

    Ingredients: salicylic acid - 2 g; zinc oxide - 10 g.

    Instructions
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