Sanguirythrin - instructions for use, dose, side effects, contraindications

Active substanceSanguinarina Hydrosulfate + Helerythrina HydrosulfateSanguinarina Hydrosulfate + Helerythrina Hydrosulfate

Similar drugsTo uncover

Sanguirythrin®

pills inwards

FARMTSENTR VILAR, ZAO Russia

Sanguirythrin®

solution locally externally

FARMTSENTR VILAR, ZAO Russia

Dosage form: & nbspTablets, covered with enteric coating.

Composition:

Composition per one tablet

Active substance:

Sanguirythrin® in terms of 100% substance 0.005 g

(Sanguinarina hydrogen sulphate + Helerythrins hydrogensulfate)

Excipients (core): Sugar (sucrose) or refined sugar, povidone low molecular weight - to obtain a core mass (polyvinylpyrrolidone low molecular weight medical 12600 ± 2700), magnesium stearate 0.100 g

Shell accessories: opedraj II white OY-LS-28911, acrylic white 93018359, opedraj II - before receipt of the tablet, red 85F25163 coated coat,

with a mass of 0.110 g

Notes.

1. Composition of opaque II white OY-LS-28911.

Hydroxypropylmethylcellulose (hypromellose) 28-40%

Lactose monohydrate 21 - 40% or

Polydextrose 21-40%

Polyethylene glycol 4000 (macrogol 4000) 8-14%

Dye - titanium dioxide 20-30%

2. Composition of acrylic white 93Q18359.

A copolymer of methacrylic acid with ethyl acrylate 1: 1 40.0%

Titanium dioxide 15.0%

Talc 37.25%

Triethyl citrate 4.8%

Silicon dioxide colloidal anhydrous 1.25%

Sodium bicarbonate 1.2%

Sodium lauryl sulfate 0.5%

3. Composition of the opaque II red 85F25163.

Hydroxypropylmethylcellulose (hypromellose) 28-40%

Lactose monohydrate 21 - 40% or Polydextrose 21 - 40%

Polyethylene glycol 4000 (macrogol 4000) 8-14%

Dye - iron oxide red, E 172 20 - 30%

Description:Round tablets with biconvex surfaces covered with a film membrane, from dark orange to brownish-orange color.

Pharmacotherapeutic group:Antimicrobial agent of plant origin.

ATX: & nbsp

J.01.X.X Other antibacterial drugs

Pharmacodynamics:

Sanguirythrin® is derived from the Macleaya cordata (Willd.) R.Br. Macleaya cordata (MacDonald.RTM.) And Macleaya microcarpa (Maxim.) Fedde) poppy families - Papaveraceae. Sangviritrin® is a mixture of bisulfates of two quarantine benzophenanthridine alkaloids of similar structure and properties, selvinarin and chelerythrine.

The drug has a wide spectrum of antimicrobial activity, acting on Gram-positive and Gram-negative bacteria, pathogenic fungi, yeast-like mushrooms of the genus Candida, including multiresistant strains of microorganisms, as well as actinomycetes and some pathogenic protozoa. At the core of the mechanism of antimicrobial action of the drug is the suppression of bacterial nuclease, a violation of the permeability of cell walls. The drug also has a weak anticholinesterase action.

Indications:In the complex therapy of acute and chronic purulent-inflammatory diseases: acute intestinal infections (dysentery, salmonella, food-borne diseases), wound infections and various infectious complications caused by pathogenic microflora (convalescence bacteriocarrier), diseases associated with violation of normal microflora (dysbacteriosis), and also diseases caused by pathogenic fungi (pharyngicosis, candidiasis, microsporia).

Contraindications:Hypersensitivity to the drug components, epilepsy, hyperkinesia, bronchial asthma, coronary heart disease, severe liver and kidney disease with impaired function. Children up to 3 years.

Pregnancy and lactation:The use of the drug during pregnancy and during breastfeeding is possible in view of the expected benefits for the mother and the potential risk to the fetus / child. It is necessary to consult a doctor.

Dosing and Administration:

Tablets are taken orally (not chewing!) after eating.

Adults usually appoint 2 (10 mg) tablets 3-4 times a day (if necessary, the daily dose can be increased to 9 tablets).

Children 10-15 years old are prescribed 1-2 (5 - 10 mg) tablets 3 times a day (maximum daily dose - up to 6 tablets).

Children 5-10 years - 1 tablet (5 mg) 3-4 times a day (maximum daily dose - up to 4 tablets).

Children 3-5 years - 1 tablet (5 mg) 2-3 times a day (the maximum daily dose is up to 3 tablets).

The duration of treatment depends on the nosological form and severity of the disease and is, on average:

- with acute intestinal infections (dysentery, salmonellosis, food poisoning) - 5-7 days (if necessary, up to 10 days);

- with dysbacteriosis - up to 10-14 days;

- at bacteriocarrier (bacterial release) - 7-14 days; with pharyngomycosis and candidiasis - up to 14 days; with microsporia for 4-5 weeks.

Conducting repeated courses of treatment is possible on the recommendation of a doctor.

Side effects:There may be allergic reactions. When chewing the tablets, dyspeptic phenomena (nausea, vomiting), abdominal pains are possible.

Overdose:

With an overdose of the drug, nausea, vomiting, abdominal pain, dizziness, headache are possible.

In case of an overdose, a gastric lavage should be performed. Treatment is symptomatic.

Interaction:Not described.

Special instructions:

Information for patients with diabetes mellitus:

In a single dose, the drug contains 93.7 mg of sugar (sucrose) or sugar-refined sugar, which corresponds to 0.008 XE.

Form release / dosage:

Tablets, coated with enteric coating, 5 mg.

Packaging:

For 10, 30 or 50 tablets per contour cell package.

For 3 or 5 contour packs of 10 tablets each, or 1 circuit pack of 30 or 50 tablets together with the instructions for use are placed in a pack of cardboard for consumer containers.

Storage conditions:List B. In a dry, the dark place at a temperature of no higher than 25 ° C. Keep out of the reach of children.

Shelf life:

3 years.

Do not use after the expiration date.

Terms of leave from pharmacies:Without recipe

Registration number:LSR-005094/10

Date of registration:01.06.2010

The owner of the registration certificate:FARMTSENTR VILAR, ZAO FARMTSENTR VILAR, ZAO Russia

Manufacturer: & nbsp

FARMTSENTR VILAR, ZAO Russia

Information update date: & nbsp17.08.2015

Illustrated instructions

Instructions

Sanguirythrin® (Sanguiritrin®)