Combined drug, has the properties of its active components - antibiotic and glucocorticosteroid.
Tobramycin - antibacterial agent from the group of aminoglycosides (2nd generation). Suppress the growth and development of gram-negative and gram-positive microorganisms. Blocks the 30-S subunit in the ribosome and stops the synthesis of the protein. At higher concentrations, it disrupts the function of cytoplasmic membranes, causing cell death.
The drug is active against gram-positive bacteria (staphylococci - Staphylococcus aureus, Staphylococcus epidermidis, Citrobacter Species, Enterobacter Species) and Gram-negative bacteria (Escherichia coli, Klebsiella Species, Morganella Morganii, Pseudomonas aeruginosa, Proteus mirabili, Proteus vulgaris, Providensia spp, Serratia spp).
Dexamethasone - fluorinated glucocorticosteroid, which has a pronounced anti-inflammatory, antiallergic and immunosuppressive action. When applied locally, it removes itching and constricts vessels. Interacts with specific cytoplasmic receptors and forms a complex penetrating the nucleus of the cell, and stimulating the synthesis of mRNA. Prevents the release of inflammatory mediators from eosinophils and mast cells. It inhibits the activity of hyaluronidase, collagenase and proteases. Reduces the permeability of capillaries, stabilizes cell membranes.