Local. In 1-10% of cases: a feeling of discomfort in the eyes, pain and irritation of the eyes. In 0.1-1% of cases: hypersensitivity and allergic reactions, increased intraocular pressure, keratitis (including acupressure), conjunctival hyperemia, pruritus, erythema eyelids, blurred vision, sensation of foreign body in the eye, edema of the eyelids and conjunctiva, syndrome " dry eye ", increased lacrimation. The frequency is unknown: the development of glaucoma, cataracts, decreased visual acuity, mydriasis, photophobia.
System. In 0.1-1% of cases: headache, dysgeusia, laryngospasm, rhinorrhea.
With prolonged use (more than 24 days) or an increase in the frequency of instillations of glucocorticosteroids, there may be: increased intraocular pressure with possible subsequent development of steroid glaucoma; posterior subcapsular cataract, slowing down the process of wound healing (with diseases that cause thinning of the cornea, its perforation is possible).
Secondary infection. Secondary bacterial infection may occur as a consequence of local immunosuppressive effects of glucocorticosteroids. Fungal infection of the cornea tends to occur especially often with prolonged use of glucocorticosteroids. The appearance of non-healing ulcers on the cornea after prolonged treatment with glucocorticosteroids may indicate the development of a fungal infection. In acute purulent diseases of the eye, glucocorticosteroids can mask or strengthen the existing infectious process.