In adults: Cytoflavin® is used only intravenously drip in dilution for 100-200 ml of 5-10% dextrose solution or 0.9% solution of sodium chloride.
With acute impairment of cerebral circulation the drug is administered as soon as possible from the onset of the development of the disease in a volume of 10 ml for administration at an interval of 8-12 hours for 10 days. With a severe form of the disease, a single dose is increased to 20 ml.
With the consequences of cerebrovascular diseases (the consequences of cerebral infarction, cerebral atherosclerosis) the drug is administered in a volume of 10 ml per administration once a day for 10 days.
With toxic and hypoxic encephalopathies the drug is administered in a volume of 10 ml for administration twice a day after 8-12 hours for 5 days. In a comatose state in a volume of 20 ml per injection in a dilution of 200 ml of a solution of dextrose.
With post-canker depression once in the same doses.
In the treatment of hypoxic encephalopathy cardiosurgery operations using of artificial circulation, 20 ml of the drug are diluted in 200 ml of dilution 5% solution of dextrose 3 days prior to surgery, on the day of surgery, 3 days after the operation.
Children (including prematurity) in the neonatal period with cerebral ischemia, the daily dose of CITOFLAVIN® is 2 ml / kg / day. The calculated daily dose of the drug is administered intravenously drip (slowly) after dilution in a 5% or 10% solution of dextrose (in a ratio of not less than 1: 5). The time of the first administration is the first 12 hours after birth; The optimal time to start therapy is the first 2 hours of life. It is recommended to inject the prepared solution with an infusion pump at a rate of 1 to 4 ml / h,ensuring a uniform supply of the drug in the bloodstream during the day, depending on the estimated daily volume of solutions for basic therapy, the patient's hemodynamic state, and the acid-base state. The average course of treatment is 5 days.