Active substanceCytochrome CCytochrome C
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  • Cytochrome C
    solution w / m in / in 
    SAMSON-MED, LLC     Russia
  • Dosage form: & nbspLyophilizate for the preparation of solution for intravenous and intramuscular administration
    Composition:Cytochrome C - 10 mg
    Excipients: sodium chloride
    Description:Lyophilized powder or porous mass, compacted into a tablet, is a pinkish-brown color.
    Pharmacotherapeutic group:Metabolic means
    ATX: & nbsp

    C.01.C.X   Other cardiotonic drugs

    Pharmacodynamics:Metabolic means, has antihypoxic, trophic action, stimulates regeneration processes. It is a catalyst for cellular respiration. The mechanism of action of the drug is associated with the presence in the prosthetic group of iron, capable of transitioning from an oxidized state to a reduced one. As a result, endogenous oxidation-reduction reactions and metabolic processes in tissues are accelerated, oxygen utilization is improved and hypoxia of tissues is reduced under various pathological conditions.
    Pharmacokinetics:Quickly and completely absorbed. Well penetrates into cells of organs and tissues.
    Indications:Cytochrome-C is used in complex therapy as a means of improving tissue respiration,at conditions accompanied by disturbance of oxidation-reduction processes in the body: asphyxia of newborns; severe injuries; before and after surgery (to prevent shock), during the remission of bronchial asthma with respiratory failure, in patients with chronic obstructive pulmonary disease and heart failure; with viral hepatitis complicated by a hepatic coma; when poisoning with hypnotic drugs and carbon monoxide.
    Contraindications:Hypersensitivity to the drug, pregnancy, lactation.
    Dosing and Administration:The drug is taken intravenously and intramuscularly. Before using Cytochrome-C, the contents of the vial should be dissolved in 4 ml of water for injection and determine the individual sensitivity to it. To this end, 0.1 ml of the preparation (0.25 mg) is injected intradermally. If the reaction does not occur within 30 minutes (red face, itchy skin, urticaria), then you can start treatment with the drug. Before prescribing a repeated course, you must repeat the biological test.
    The drug is administered intravenously slowly or intramuscularly in an amount of 10-20 mg 1 to 2 times a day.The course of treatment is 10-14 days.
    With heart failure, the drug is diluted in 200 ml of isotonic sodium chloride solution or 5% glucose solution and injected intravenously (30-40 drops per minute) for 6-8 hours. The daily dose is 30-80 mg.
    In the postoperative period (surgery for congenital and acquired heart defects), the drug is administered intravenously twice a day for 10 mg per injection. In case of a serious condition (trauma, shock, hepatic coma, poisoning with hypnotic drugs and carbon monoxide), the drug is prescribed in an amount of 50-100 mg.
    In asphyxiated infants, the drug is injected into the umbilical vein during the first two minutes after birth at a dose of 10 mg.
    In bronchial asthma, the drug is administered intramuscularly 2 times a day at a dose of 5-10 mg per injection. The course of treatment lasts from 14 to 25 days, depending on the severity of hypoxia.

    Side effects:With the rapid administration of the drug may occur chills with fever, allergic reactions. With prolonged use are possible: a change in the pattern of peripheral blood; indicators of the blood coagulation system; function of the liver.
    Interaction:Not described.
    Form release / dosage:Lyophilizate for the preparation of a solution for intravenous and intramuscular administration of 10 mg.
    Packaging:Lyophilizate for the preparation of a solution for intravenous and intramuscular injection in vials of 5 ml capacity containing 10 mg of the drug. 5 bottles per blister of PVC film, 1 or 2 blisters in a pack of cardboard with instructions for use.
    Storage conditions:In a dry place protected from light, at a temperature not exceeding 20 ° C.
    Keep out of the reach of children.
    Shelf life:2 years.
    Do not use after expiry date.
    Terms of leave from pharmacies:On prescription
    Registration number:LSR-008117/08
    Date of registration:14.10.2008
    The owner of the registration certificate:SAMSON-MED, LLC SAMSON-MED, LLC Russia
    Manufacturer: & nbsp
    Information update date: & nbsp08.09.2015
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