Vaccine for the prevention of herpetic infections (Vaccinum ad prophylaxim herpetis)

Pharmacodynamics Pharmacokinetics Indications Carefully Contraindications Dosing and Administration Side effects
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Clinical and pharmacological group: & nbsp

Vaccines, serums, phages and toxoids

Included in the formulation
  • Vitaherpavak
    lyophilizate in / skin 
    VITAFARMA FIRM, CJSC     Russia
  • Gerpovax
    lyophilizate in / skin 
    SPbNIIVS FMBA, FSUE     Russia
    • АТХ:

    J.07.B.X   Other vaccines for the prevention of viral infections

    Pharmacodynamics:

    The inactivated herpes simplex virus of the 1st and 2nd antigenic types, obtained by reproduction in Vero B cell culture, lyophilized.

    Stimulates the cellular mechanisms of resistance of the human body to the herpes simplex virus of the first and second types.

    Pharmacokinetics:

    No data.

    Indications:

    Prevention of recurrence of herpetic infection.

    ICD-10

    I.B00-B09.B00   Infections caused by the herpes simplex virus [herpes simplex]

    Contraindications:

    Hypersensitivity to gentamicin and other antibiotics of the aminoglycoside group; herpetic infection in the active stage (vaccination is performed no earlier than 5 days after the disappearance of clinical manifestations, with ophthalmoherpes - no earlier than 1 month); acute (infectious and non-infectious) diseases; chronic diseases in the stage of exacerbation or decompensation; malignant neoplasms; pregnancy.

    Carefully:

    The vial is opened, the drug is dissolved and the vaccination procedure is carried out under strict observancerules of asepsis.

    Pregnancy and lactation:

    Contraindications to use during pregnancy.

    Dosing and Administration:

    Intradermically, the area of ​​the inner surface of the forearm in a single dose of 0.2 ml (control - the formation of "lemon crust").

    The course of vaccination for herpes infections of the skin and mucous membranes - 5 injections, which are carried out with an interval of 7 days.

    Patients with a complicated herpetic infection second and subsequent injections are repeated with an interval of 10 days. After 6 months, repeat a course of vaccination (5 injections).

    The contents of the vial are dissolved in 0.3 ml of solvent (water for injections). To do this, the solvent is injected into the vial of the vaccine using a syringe with a needle, which is then shaken until the contents are completely dissolved.

    Side effects:

    Are common: a slight increase in temperature, weakness.

    Local reaction: hyperemia of the skin up to 2 cm in diameter during the first day and a slight short-term burning (normal reaction of the body to the introduction of the vaccine).

    Overdose:

    No data.

    Interaction:

    There is no reliable data on the drug interaction of the drug with other drugs.

    Special instructions:

    Vaccination is carried out in medical institutions (hospital, dispensary, polyclinic) under the supervision of a doctor.

    Vaccination is performed in the remission stage, not earlier than 5 days after the complete disappearance of clinical manifestations of herpetic infection.

    If more severe local and general reactions occur or if the main process is exacerbated, vaccination should be discontinued. Vaccination can be continued after the complete disappearance of clinical manifestations of the overall response to the introduction of the vaccine.

    All cases of more pronounced local and general reactions in the patient should be examined by a doctor and recorded in the relevant document.

    The dissolved preparation should be a slightly opalescent liquid of pink color.

    The preparation is not suitable for use in vials with broken integrity, marking, when the color changes, with expired shelf life, if stored incorrectly.

    The dissolved vaccine is not subject to storage.

    Opening of the vial, dissolution of the drug and the vaccination procedure are carried out with strict adherence to aseptic rules.

    Instructions
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