The vaccine is administered intranasally two times with an interval of 10 days by means of a dispenser - dispenser (RD).
Immediately before vaccination, the contents of the ampoule are dissolved at room temperature in 0.5 ml of the solvent included in the vaccine kit. The vaccine should completely dissolve within three minutes. Dissolved drug - colorless, slightly opalescent liquid.
It is not suitable to use the drug in ampoules with broken integrity, marking, as well as changing its physical properties (color, transparency), with improper storage.
The vaccine is injected into the nasal passages at a rate of 0.25 ml per each nasal opening. To administer the vaccine in the form of a finely divided mixture, a sterile syringe, a sterile needle and one removable nozzle single use, included in the kit vaccine.
The spray tip is injected to a depth of 0.5 cm into the nasal passages, previously cleaned of mucus. The grafted should be in a sitting position with a slightly upturned head. After vaccine administration, the vaccine should remain in a sitting position with a slightly tilted head for 1 minute. Dissolved vaccine should be used within 30 minutes.
Method of use for vaccination:
1. Put the needle on the syringe, fill it with a solvent (water for injections) of room temperature, included in the vaccine kit, in a volume of 0.5 ml.
2. For dissolution, fill the opened ampoule with the vaccine with a solvent from the syringe.
3. After dissolution, fill the syringe with 0.5 ml (mark 20 on a scale of 80 units or mark 50 on a scale of 100 units).
4. Remove the needle and put on a tightly detachable nozzle (spray tip).
5. Bring the nozzle tip close to the nasal passage and squeeze the vaccine into each nasal passage of 0.25 ml with sharp pressure on the syringe plunger.