Validol with glucose (Validol with glucosae)

Composition Pharmacodynamics Indications Carefully Contraindications Dosing and Administration Side effects Form release / dosage
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Dosage form: & nbspsublingual tablets
Composition:

1 tablet contains

active substances: levomenthol solution in Mentyl isovalerate [Validol] 0.060 g

dextrose monohydrate [glucose monohydrate] (in terms of anhydrous substance) 0.171 g

Excipients: povidone - 0.049 g, potato starch - 0.023 g, sucrose [sugar] - 0.489 g, calcium stearate - 0.008 g to obtain a tablet weighing 0.8 g

Description:

Tablets white or white with grayish splashes of color, with a characteristic smell of menthol, round, flat-cylindrical, with a risk and facet.

Pharmacotherapeutic group:Coronarodilating agent of reflex action
ATX: & nbsp
  • Other combination drugs for the treatment of heart disease
    • Pharmacodynamics:

    Validol has a calming effect on the central nervous system, as well as a moderate reflex vasodilator effect, caused by irritation of sensitive nerve endings. Stimulates production and release enkephalins, endorphins and a number of other peptides, histamine, kinin (due to irritation receptors of the mucosa), which take an active part in the regulation of vascular permeability, the formation of pain. With sublingual admission, the therapeutic effect on average occurs in 5 minutes, while up to 70% of the drug is released within 3 minutes.

    Dextrose is involved in various metabolic processes in the body, in particular, enhances oxidation-reduction processes.

    Pharmacokinetics:

    In sublingual use, it is absorbed from the oral mucosa, metabolized in the liver, excreted by the kidneys in the form of glucuronides.

    Indications:

    Functional cardialgia, neurosis, "motion sickness" syndrome (nausea, vomiting in sea and air sickness).

    Contraindications:

    Hypersensitivity to the drug components, sucrose / isomaltose deficiency, fructose intolerance, glucose-galactose malabsorption.

    Age under 18 years (no data on safety and efficacy of use in children).

    Carefully:

    Diabetes.

    Pregnancy and lactation:

    Possible use of the drug during pregnancy. It should be refrained from using the drug during breastfeeding.

    Dosing and Administration:

    Validol with glucose is prescribed under the tongue. The tablet should be kept in the mouth under the tongue until completely dissolved. Take 1 tablet 2-3 times a day.

    If the effect is not sufficiently pronounced or when the effect is not observed in individual patients within the next 5 minutes after taking the drug,it is necessary to consult your doctor for other therapy.

    Side effects:

    With prolonged admission, occasionally mild nausea, lacrimation, dizziness may occur. These phenomena usually pass by themselves.

    If any of the side effects listed in the manual are aggravated, or if you notice any other side effects not listed in the instructions, inform the doctor about it.

    Overdose:

    Symptoms: headache, nausea, agitation, impaired heart activity (changes in heart rate), lowering blood pressure, suppressing the central nervous system.

    Treatment: cancel the drug. Symptomatic therapy.

    Interaction:

    When combined with neurotropic agents of depressive type of action strengthens the inhibitory effect of the latter on the central nervous system.

    Simultaneous application of Validol with glucose with nitrates reduces the headache, which arises when they are applied.

    Special instructions:

    The composition of the drug includes carbohydrates - dextrose, sucrose (1 tablet contains 0.058 XE carbohydrates), which should be taken into account by patients with diabetes mellitus.

    Effect on the ability to drive transp. cf. and fur:

    When ingesting, care should be taken when controlling vehicles and other mechanisms that require increased concentration and speed of psychomotor reactions.

    Form release / dosage:

    Tablets are sublingual.

    Packaging:

    For 6, 10 tablets in a contour mesh box made of polyvinylchloride film and aluminum foil printed lacquered.

    By 10, 20, 30, 40, 50, 60 tablets in cans of polymeric.

    Each bank or 1, 2, 3, 4, 5 contour squares with instructions for use are placed in a cardboard pack.

    Storage conditions:

    In a dry place at a temperature of no higher than 15 ° C.

    Keep out of the reach of children.

    Shelf life:

    2 years.

    Do not use after the expiration date.

    Terms of leave from pharmacies:Without recipe
    Registration number:P N003928 / 01
    Date of registration:05.03.2010 / 18.05.2012
    Expiration Date:Unlimited
    The owner of the registration certificate:URALBIOFARM, OJSC URALBIOFARM, OJSC Russia
    Manufacturer: & nbsp
    Information update date: & nbsp19.01.2017
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