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Dosage form: & nbspsublingual tablets
Composition:

1 tablet contains:

Levomenthol solution in menthyl isovalerate - 60 mg

Dextrose (glucose) -188 mg

Excipients: calcium stearate, sucrose (sugar) - to obtain a tablet weighing 800 mg.

Description:

Tablets are white with a yellowish tint of color, with grayish patches, flat-cylindrical, with a risk and facet, with a characteristic smell of menthol.

Pharmacotherapeutic group:Coronarodilating agent of reflex action
Pharmacodynamics:

Has a sedative effect, has a moderate reflex vasodilator effect due to irritation of sensitive nerve endings. It stimulates the production and release of enkephalins, endorphins and a number of other peptides, kinins (due to stimulation of mucosal receptors), which take an active part in the regulation of vascular permeability, the formation of pain. With sublingual admission, the therapeutic effect on average occurs in 5 minutes, while up to 70% of the drug is released within 3 minutes.

Dextrose (glucose) is involved in various metabolic processes in the body, increases oxidation-reduction processes in the body.

Pharmacokinetics:

With sublingual use, it is absorbed from the mucous membrane of the oral cavity. After absorption, biotransformed in the liver and excreted by the kidneys in the form of glucuronides. Dextrose completely absorbed by the body, the kidneys are not excreted (appearance in the urine is a pathological sign).

Indications:

Functional cardialgia, neuroses, and also as an antiemetic for sea and air sickness.

Contraindications:

Hypersensitivity to the components of the drug.

Carefully:

With caution, appoint patients with diabetes mellitus (the drug contains sugar).

Dosing and Administration:

Validol is prescribed to adults under the tongue. The tablet should be kept in the mouth under the tongue until it is completely resorbed. Take 1 tablet 2-3 times a day.

The daily frequency and duration of reception is determined depending on the effectiveness of treatment. If the effect is not sufficiently pronounced or when the effect is not observed in the next 5 minutes after taking the drug, it is necessary to contact the attending physician to prescribe another therapy.

Side effects:

With prolonged admission, mild nausea, lacrimation, dizziness may occur.These phenomena usually pass by themselves.

Overdose:

Symptoms: headache, nausea, agitation, a violation of the heart, a drop in blood pressure, depression of the central nervous system.

Treatment: cancel the drug. Symptomatic therapy.

Interaction:

When combined with neurotropic drugs, the oppressive type of action enhances the inhibitory effect of the latter on the central nervous system.

The simultaneous use of Validol with glucose and nitrates reduces the headache that occurs when they are used.

Special instructions:

One tablet contains 188 mg of dextrose, which corresponds to 0.018 XE, which should be taken into account by a patient with diabetes mellitus.

Form release / dosage:

Tablets are sublingual.

Packaging:

For 10 tablets in a contour mesh box made of polyvinylchloride film and aluminum foil printed lacquered.

1, 2, 4, 6, 10 contour mesh packages together with the instruction for use are placed in a pack of cardboard or a hermetically sealed plastic bag made of light-proof polyethylene film or a bag of material combined on paper and cardboard basis with polyethylene coating or a material of combined "Buffalo".

5, 10, 20, 50, 100, 200, 400, 500, 600 contour squares, together with an equal number of instructions for use in a hermetically sealed polyethylene bag made of light-proof polyethylene film.

It is allowed to put the full text of instructions for use on the package, package.

Polyethylene bags are placed in a cardboard box.

Storage conditions:

In a dry place at a temperature of no higher than 25 ° C.

Keep out of the reach of children.

Shelf life:

3 years. Do not use after the expiration date.

Terms of leave from pharmacies:Without recipe
Registration number:LSR-000078/10
Date of registration:15.01.2010 / 12.04.2010
Expiration Date:Unlimited
The owner of the registration certificate:LYUMI, LLC LYUMI, LLC Russia
Manufacturer: & nbsp
Information update date: & nbsp19.01.2017
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