Has vasodilator, antihypoxic and antiaggregatory action. Inhibits phosphodiesterase and increases the content of cyclic adenosine monophosphate in cells, which in turn,leads to a decrease in the calcium content in the cytoplasm of smooth muscle cells and relaxation of myofibrils. It combines vascular and metabolic actions. It dilates the vessels of the mole, increases blood flow, mainly in ischemic areas, improves the supply of oxygen to the brain. Promotes the initialization of glucose and increases the level of catecholamines in the central nervous system, stimulates the metabolism of norepinephrine and serotonin in the brain tissues. Reduces platelet aggregation, blood viscosity, promotes increased erythrocyte deformability and normalization of venous outflow against a background of decreased resistance of cerebral vessels. Systemic blood pressure slightly decreases. Effective in the acute period of stroke: accelerates the regress of cerebral and focal neurological symptoms, improves memory, attention, intellectual productivity. In the elderly and senile age, the sensitivity of the cerebral vessels to the relaxing action of vinpocetin increases, which is due to the sensitization of the adenylate cyclase system - cyclic adenosine monophosphate upon aging.
Quickly absorbed from the gastrointestinal tract, bioavailability of about 60%.
The maximum concentration in the blood plasma is reached after 1 hour. Easily diffuses through the cystogematic barriers (including through the blood-brain barrier) and penetrates into the tissues. Half-life is about 5 hours.