Vitagamma - instructions for use, dose, side effects, contraindications

Pharmacological action is determined by the properties that make up the preparation of the components. Vitamins B₁, AT₆ and B₁₂ regulate protein, carbohydrate and fat metabolism, promote its normalization, improve the function of motor, sensory and autonomic nerves.

Thiamine (B₁) prevents protein glycolation, has antioxidant activity, participates in the regulation of nerve impulses.

Pyridoxine (B₆) participates in the synthesis of neurotransmitters (dopamine, norepinephrine, etc.), the reactions of decarboxylation, de-and reamination of amino acids, prevents the accumulation of ammonia and accelerates the regenerative processes in the nervous tissue.

Cyanocobalamin (B₁₂) is necessary for normal hematopoiesis, participates in the synthesis of myelin tissue.

Pharmacokinetics:

Indications:

Neurological diseases due to a proven vitamin B deficiency₁, AT₆ and B₁₂.

As an auxiliary for symptomatic therapy of diseases of the nervous system of various origins: neuritis and polyneuritis (including those accompanied by pain syndrome), incl. retrobulbar neuritis, peripheral paresis (including facial nerve), neuralgia, polyneuropathy (diabetic, alcoholic, etc.).

Contraindications:Hypersensitivity to the components of the drug; pregnancy and the period of breastfeeding; thrombosis and thromboembolism; severe forms of decompensated heart failure; erythremia, erythrocytosis, severe bleeding, arterial hypotension, shock conditions, children's age.

Carefully:

Encephalopathy Wernicke, premenopausal and climacteric period in women, severe angina, benign and malignant neoplasms, accompanied by megaloblastic anemia and vitamin B deficiency₁₂, propensity to form blood clots, elderly age (over 65 years).

Dosing and Administration:

Deep intramuscularly, in severe cases and with acute pain, 2 ml are administered daily. After the exacerbation has passed or at light forms of the disease 2-3 times a week are administered 2 ml each.

Side effects:

In some cases, there may be increased sweating, tachycardia, acne. Cases of development of skin allergic reactions (itching, urticaria and other skin rash), as well as systemic reactions (shortness of breath, Quincke's edema, anaphylactic shock) are described.

In the case of very rapid administration of the drug may occur: dizziness, headache, vomiting, tachycardia or bradycardia, arrhythmia, convulsions, agitation, cardialgia.

Overdose:In case of overdose, symptoms of side effects of the drug increase, symptomatic therapy is performed.

Interaction:

Thiamin is destroyed in solutions containing sulfites.

Therapeutic doses of vitamin B₆ reduce the effect of levodopa.

Copper ions, pH values greater than 3, accelerate the breakdown of thiamine.

Vitamin B₁₂ is incompatible with salts of heavy metals. In solutions containing thiamine, cyanocobalamin (like other B vitamins) is rapidly destroyed (low concentrations of iron ions present in the drug can prevent this).

Form release / dosage:

Solution for intramuscular injection in ampoules 2 ml.

Packaging:

5 ampoules per contour cell pack. 1, 2 contour mesh packages together with the instructions for use and a vial ampoule or scarifier ampullum is placed in a pack of cardboard. If you use ampoules with a dot, the fracture ring, the ampoule opener or the scarifier is not inserted.

Storage conditions:

In a place protected from light, out of reach of children, at a temperature not exceeding 15 ° С.

Shelf life:2 years. Do not use after the expiration date indicated on the package.

Terms of leave from pharmacies:On prescription

Registration number:P N003491 / 01

Date of registration:18.06.2009

Expiration Date:Unlimited

The owner of the registration certificate:BRYNTSALOV-A, CJSC BRYNTSALOV-A, CJSC Russia

Manufacturer: & nbsp

BRYNTSALOV-A, CJSC Russia

Information update date: & nbsp21.02.2017

Illustrated instructions

Instructions

Vitagamma (Vitagamma)