Anti-Angin® Formula (Anti-Angin® Formula)

Composition Pharmacodynamics Indications Carefully Contraindications Dosing and Administration Side effects Form release / dosage
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Active substanceTetracaine + Chlorhexidine + Ascorbic acidTetracaine + Chlorhexidine + Ascorbic acid
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  • Anti-Angin® Formula
    pills n / az. 
    VALEANT, LLC     Russia
  • Anti-Angin® Formula
    lozenges
    VALEANT, LLC     Russia
    • Dosage form: & nbsplozenges
    Composition:

    Composition per lozenge:

    Active substances:

    Chlorhexidine diacetate 2.00 mg

    Tetracaine hydrochloride 0.20 mg

    Ascorbic acid 50.00 mg

    Excipients: dextrose syrup, sucrose, levomenthol, flavor mint oil, anethole, banana flavor, carmine red dye E 120, purified water.

    Description:Flat round, with a bevelled edge of a lozenge with a roughened surface from pink to a pinkish-red color with a specific smell. Allowed uneven staining, the presence of air bubbles in the caramel mass and a slight unevenness of the edges.
    Pharmacotherapeutic group:Antiseptic + local anesthetic
    ATX: & nbsp

    R.02.A.A.20   Other drugs

    R.02.A   Drugs for the treatment of throat diseases

    Pharmacodynamics:

    Chlorhexidine has a bactericidal and bacteriostatic effect.

    Has a broad antibacterial spectrum of action against Gram-positive and Gram-negative bacteria, is active against Candida albicans. Chlorhexidine is especially active in Streptococcus mutans, Streptococcus salivarius, Escherichia coli and anaerobic bacteria. Less effective against such microorganisms as Streptococcus spp., Proteus spp., Pseudomonas spp., Klebsiella spp., Veillonella spp.

    Anesthetic Tetracaine, has a local anesthetic effect. The anesthetic effect occurs 1-2 minutes after application.

    Ascorbic acid is involved in the process of collagen synthesis and tissue regeneration, regulation of oxidation-reduction processes, enhances immune responses. By reducing the permeability of capillaries, it helps to reduce inflammation and edema of the mucous membranes of the mouth and pharynx.

    Pharmacokinetics:
    Indications:

    Prevention and treatment of infectious and inflammatory diseases of the oral cavity and pharynx (including tonsillitis, pharyngitis, the initial stage of angina, stomatitis, gingivitis, periodontitis, conditions after tonsillectomy or tooth extraction).

    Contraindications:Hypersensitivity to the components of the drug, children under 5 years of age, I trimester of pregnancy, sugar / isomaltase deficiency, fructose intolerance, glucose-galactose malabsorption, hypersensitivity (including to other local anesthetic drugs group of esters or para-aminobenzoic acid and its derivatives).
    Carefully:In the second and third trimesters of pregnancy according to the doctor's prescription, during the period, lactations, diabetes mellitus, deficiency of glucose-6-phosphate dehydrogenase, hemochromatosis, sideroblastic anemia, thalassemia, hyperoxaluria, oxalose and urolithiasis.
    Dosing and Administration:

    Locally. Slowly dissolve until completely dissolved in the mouth.

    Adults and children from 15 years: 1 lozenge every 2 hours, but not more than 6 lozenges per day.

    - Children from 10 to 15 years: 1 lozenge every 3 hours, but not more than 4 lozenges per day.

    - Children from 5 to 10 years: 1 lozenge every 4 hours, but not more than 3 lozenges per day.

    The course of treatment is no more than 5 days.

    Side effects:

    Allergic reactions are possible (in patients with increased sensitivity to the components of the drug).

    Exceeding the recommended period of therapy can cause a brief disruption of taste); it is also possible to damage the tooth enamel (staining, deposition of tartar).

    Overdose:

    Symptoms: dizziness, general weakness, cyanosis, agitation, restlessness, muscle tremor, respiratory failure, nausea, vomiting.

    Treatment: gastric lavage, the appointment of salt laxatives; symptomatic therapy.

    Interaction:

    Chlorhexidine is not compatible with detergents containing an anionic group (saponins, sodium lauryl sulfate, sodium carboxymethyl cellulose). Not recommended - simultaneous use with iodine. Ethanol enhances the effect of the drug. Tetracaine reduces the antibacterial activity of sulfanilamide preparations. Vasoconstrictors extend the effect and reduce the toxicity of tetracaine. Ascorbic acid increases the concentration in the blood of benzylpenicillin and tetracyclines. Improves the absorption of iron in the intestine. Reduces the effectiveness of heparin and indirect anticoagulants. Increases the risk of developing crystalluria in the treatment of salicylates and sulfonamides short-acting, reduces the concentration in the blood of oral contraceptives.

    Special instructions:

    It is not recommended to apply simultaneously with oral and pharyngeal preparations containing iodine (Lugol's solution, povidone-iodine). Ascorbic acid, which is a part of the preparation, can change the results of some laboratory tests, which should be reported during the analysis.

    Patients with diabetes should take into account that in one lozenge contains 1.4 g of sucrose, which corresponds to 0.12 XE.

    The use of the drug for more than 5 days is undesirable because of a possible violation of the normal microflora of the oral cavity and pharynx. Do not take the lozenges immediately before eating or while eating. After taking the drug is not recommended to brush your teeth, because the surfactants in the toothpaste can inactivate chlorhexidine. The drug may affect the results of the anti-doping control.

    Effect on the ability to drive transp. cf. and fur:According to the pharmacological properties, the drug does not affect the activities that require an increased concentration of attention and speed of psychomotor reactions.
    Form release / dosage:

    Pastilles.

    Packaging:

    For 2, 4, 6, 8, 10, 12 lozenges in a PVC / A1 blister.

    For 1, 2, 3, 4, 5, 10, 15 blisters in a cardboard box with instructions for use.

    Storage conditions:

    At a temperature of no higher than 25 ° C.

    Keep out of the reach of children!

    Shelf life:

    3 years.

    Do not use after the expiration date.

    Terms of leave from pharmacies:On prescription
    Registration number:P N 015460/02
    Date of registration:12.12.2008 / 18.10.2016
    Expiration Date:Unlimited
    The owner of the registration certificate:VALEANT, LLC VALEANT, LLC Russia
    Manufacturer: & nbsp
    Representation: & nbspVALEANT LLC VALEANT LLC Russia
    Information update date: & nbsp06.09.2017
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