The drug is a combination of betamethasone and mupirocin for external use, the effect of which is due to its constituent components.
Mupirocin is an antibiotic produced by a microorganism Pseudomonas fluorescens. Mupirocin Suppresses the synthesis of the bacterial cell protein by reversible binding with isoleucyl-transport RNA synthetase, which prevents the inclusion of isoleucine in the protein chains under construction. When used in minimal inhibitory concentrations mupirocin has bacteriostatic, and in higher concentrations - bactericidal action.
Due to a specific mechanism of action and a unique chemical structure, there is no cross-resistance with other antibiotics. With the correct application of mupirocin, the risk of the emergence of resistant strains of microorganisms is small.
Betamethasone is a glucocorticosteroid for external use.
Has anti-inflammatory local, anti-allergic, anti-edematous and antiproliferative effect.Has a stronger vasoconstrictive effect than other fluoride-derived glucocorticosteroids; systemic effects are expressed only slightly due to limited absorption through the skin. When exposed to the skin, the edge accumulation of neutrophils is prevented, which leads to a decrease in exudation, production of cytokines, inhibition of migration of macrophages, leading ultimately to a decrease in the processes of infiltration and granulation.