Echinacea purpurea grass extract - instructions for use, dose, side effects, contraindications

Pharmacological action - immunostimulating. Echinacea purpurea contains active substances that enhance the natural defenses of the body and act as stimulants of immunity.

Increases nonspecific resistance of the body. Stimulates the phagocytic activity of granulocytes, macrophages. It increases the body's resistance to infectious and colds, promotes the excretion of radionuclides, increases the functional activity of bone marrow and spleen cells, enhances antibody formation.

Thanks to inulin, levulose, betaine improves metabolic processes, especially in the liver and kidneys.

In addition, the antiviral effect of the herb of Echinacea purpurea has been established in relation to the pathogens of influenza and herpes.

Pharmacokinetics:

Insufficiently investigated in humans.

Indications:

Increase nonspecific factors of body protection in uncomplicated acute infectious diseases and with a predisposition to frequent catarrhal diseases; in order to stimulate immunity in patients with uncomplicated acute infectious diseases (as an auxiliary treatment); prevention of ARVI and influenza; as an auxiliary drug for prolonged antibiotic therapy of chronic infectious diseases.

ICD-10

VIII.H60-H62.H60.3 Other infectious external otitis media

X.J10-J18.J18 Pneumonia without clarification of the pathogen

X.J20-J22.J22 Acute respiratory infection of lower respiratory tract, unspecified

X.J30-J39.J39 Other diseases of the upper respiratory tract

X.J30-J39 Other diseases of the upper respiratory tract

X.J30-J39.J39.9 Disease of upper respiratory tract, unspecified

X.J40-J47.J42 Chronic bronchitis, unspecified

X.J40-J47.J44.9 Chronic obstructive pulmonary disease, unspecified

XIV.N30-N39.N39.0 Urinary tract infection without established localization

XXI.Z20-Z29.Z29.1 Prophylactic immunotherapy

Contraindications:

Hypersensitivity to the components of the preparation and plants of the family Compositae; progressive systemic and autoimmune diseases, such as tuberculosis, leukemia, collagen, multiple sclerosis, AIDS or HIV infection; children under 1 year (for oral solution) or up to 4 years (for tablets). Pregnancy, breast-feeding.

Carefully:

For forms containing in the composition of ethanol: diabetes mellitus, chronic liver disease, chronic alcoholism, bronchial asthma, children's age (up to 12 years).

Patients with congenital intolerance to fructose can use the pill only after consulting a doctor.

Pregnancy and lactation:

Category of recommendations for FDA is not defined. Qualitative and well-controlled studies on humans and animals have not been conducted. Do not apply!

There is no information on the penetration into breast milk. Do not apply!

Dosing and Administration:

Echinacea preparations are taken internally. The dose, frequency and duration of application are set individually, depending on the dosage form used.

Side effects:

In some cases, allergic reactions are possible: rashes, itching, rarely - edema of the face, shortness of breath, sweating (require discontinuation of treatment and consultation of a doctor).

Overdose:

Symptoms: nausea, vomiting, diarrhea, insomnia, increased excitability of the nervous system.

Treatment: symptomatic.

Interaction:

Cephalosporins containing a methylthiotetrazol group (cefamandol, cefaferazone) together with Echinacea containing ethanol, can cause tetur-like reactions (nausea, sweating, headaches, palpitations). Reactions may occur 3 days after the end of cefalosporin treatment.

Echinacea preparations together with immunosuppressants (azathioprine, basiliximab, ciclosporin, daclizumab, muro-mionab, mycophenolate, tacrolimus) weaken their immunosuppressive effect (do not apply before and after transplantation).

With the simultaneous use of Echinacea preparations with econazole (vaginal cream), the action of econazole decreases. Simultaneous use is not recommended.

Special instructions:

Long-term retention of complaints, shortness of breath, fever, purulent or bloody sputum on the background of infectious diseases of the respiratory tract necessitate a doctor's consultation.

With the repeated appearance of complaints from the urinary tract, a medical examination and regular medical follow-up are necessary in the future.The presence of fever and the preservation of dysuric complaints (regardless of the presence of blood in the urine) for 5 days require a re-visit to the doctor.

During the period of application of Echinacea, no other immunostimulating drugs should be prescribed.

High doses affect the activity of sperm enzymes - reduce mobility by 24-48 hours.

The application can cause an increase in biochemical parameters: ALT, AST, the number of lymphocytes, the level of immunoglobulin E in serum, ESR, and a decrease in serum ferritin.

It is necessary to avoid prolonged, more than 8 weeks of using the drug.

In the case of long-term storage of medicinal forms in the form of aqueous extracts, turbidity may develop, a precipitate consisting of active polysaccharides appears (shake several times before use). Turbidity and flocculent formations do not affect efficiency.

Instructions

Echinacea Purple Herb Extract (Extractum herbae Echinaceae purpurae)