Exportal® (Exportale)

Composition Pharmacodynamics Indications Carefully Contraindications Dosing and Administration Side effects Form release / dosage
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Active substanceLactitolLactitol
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  • Exportal®
    powder inwards 
    FPK FarmVILAR, ZAO     Russia
    • Dosage form: & nbspPowder for solution for oral administration
    Composition: Lactitol monohydrate - 5 g or 10 g in a sachet, 200 g or 500 g in plastic containers. Without auxiliary substances.
    Description: white crystalline powder
    Pharmacotherapeutic group:Laxative.
    ATX: & nbsp

    A.06.A.D   Laxative preparations with osmotic properties

    A.06.A.D.12   Lactitol

    Pharmacodynamics:

    In the large intestine lactitol splits under the action of the flora of the intestine into low-molecular organic acids, which leads to an increase in osmotic pressure in the large intestine, an increase in the volume of feces, their softening, facilitating bowel movements and normalizing bowel function. The laxative effect usually occurs within 24 hours after application of the drug (the delay is due to the passage of the drug through the gastrointestinal tract,intestinal tract). At the beginning of the course of treatment, the laxative effect of the drug may be delayed, the effect may occur on the second or third day of its use.

    In patients with hepatic encephalopathy or hepatic coma (or precoma), the effect is achieved through the migration of ammonia from the blood to the large intestine (due to a decrease in PH, an increase in osmotic pressure in the lumen of the intestine), removal of detached ammonium ions and other nitrogen-containing toxic substances from the colon. Lactitol suppresses proteolytic bacteria and increases the number of acidophilic bacteria.

    Pharmacokinetics: Lactitol has its effect only in the large intestine, where it completely falls after ingestion. It is absorbed in minimal amounts unchanged (no more than 0.5 - 2% of the dose taken).
    Indications: Constipation, the need to regulate the stool for medical purposes (intestinal cleansing in preparation for endoscopic and radiographic research, surgery on the rectum, anal sphincter and the area adjacent to it), intestinal dysbacteriosis. Hepatic encephalopathy, hepatic precoma and coma, hyperammonia.
    Contraindications: Individual lactitol intolerance, galactosemia, intestinal obstruction, suspicion of organic damage to the gastrointestinal tract, abdominal pain and rectal bleeding of an unknown origin.
    Dosing and Administration:

    Inside with food, mixing with various drinks (water, tea, coffee, juices, etc.) or liquid food.

    With constipation and dysbiosis. The drug should be taken once, the entire daily dose at once, at one time.

    Children 1-6 years - 2.5 - 5 g (1/2 -1 teaspoon of powder) per day.

    Children 6-12 years - 5 - 10 grams (1-2 teaspoons of powder) per day.

    Children 12-16 years old - 10 - 20 grams (2-4 teaspoons of powder) per day.

    Adults: 20 g (4 teaspoons of powder) per day.

    The drug should cause a chair once a day; after the onset of a stable laxative effect for several days of the drug, its dose can be reduced. In some cases, half of the recommended daily dose is sufficient to obtain the desired effect. The minimum course of therapy, after which you should seek medical advice - 5 months. Use of the drug in

    children are recommended to be supervised by a doctor.

    When adjusting the chair for medical purposes. For 20 g of the drug, diluted in 1 liter of water, take three times (at 12, 15 and 18 hours) on the eve of medical procedures.

    With hepatic encephalopathy, hepatic precoma and coma, hyperammonemia. The dose of the drug should be selected individually for each patient, depending on the severity of the disease and individual response to the drug. The initial daily dose is usually is 0.5-0.7 g per 1 kg of body weight. This dose is divided into three single doses.Take with food. A dose should be selected, I calltwo soft chairs a day.
    Side effects:

    At the beginning of treatment, there may be a feeling of discomfort in the abdomen, flatulence. These phenomena, as a rule, disappear with the continued use of the drug, as it adapts to it.

    In the case of the use of elevated doses for a long time in the treatment of hepatic encephalopathy, the patient, due to diarrhea, may develop electrolyte imbalance.

    Overdose:

    Sign of overdose is diarrhea, in rare cases, vomiting is possible. These phenomena are usually eliminated by lowering the dose of the drug.

    Interaction:

    While taking Escortal® with enteric-soluble drugs of pH-dependent release, it should be taken into account that lactitol lowers the pH of the intestine.

    It is not recommended to use Exportsal® within two hours after taking other medicines.
    Special instructions:

    Lactitol has a low calorie content (2 kcal / g), does not affect the level of glucose in the blood and can be used in patients with diabetes mellitus.

    Throughout the course of the drug is desirable increased fluid intake.

    The use of Exportal® does not affect the psychomotor functions associated with driving a car or controlling machinery and machinery.
    Effect on the ability to drive transp. cf. and fur:The use of Exportal® does not affect the psychomotor functions associated with driving a car or controlling machinery and machinery.
    Form release / dosage: Powder for solution for oral administration. For 5 g or 10 g in single-dose bags (sachets) made of paper with polyethylene coating or from Bouflen - a combined material based on paper, aluminum and polyethylene, 2 bags are connected in 1 strip (divided perforated strip). For 3, 5, 6 or 10 strips or 6, 10, 12 or 20 bags together with the instructions for use are placed in a pack of cardboard. For 200 g or 500 g in a plastic container. Instructions for use are glued to the container.
    Storage conditions:

    In a dry place, protected from light and inaccessible to children.

    Shelf life: 5 years. Do not use at the expiration date indicated on the package
    Terms of leave from pharmacies:Without recipe
    Registration number:LSR-003898/07
    Date of registration:19.11.2007
    The owner of the registration certificate:FPK FarmVILAR, ZAO FPK FarmVILAR, ZAO Russia
    Manufacturer: & nbsp
    Information update date: & nbsp08.02.2012
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