Fer-Rhompharm is administered intramuscularly.
Intravenous administration is contraindicated.
Before the administration of each therapeutic dose, a drug tolerance test is carried out by administering 0.5-1.0 ml of Fer-Rhompharm (25-50 mg of iron) to adults, 0.4 ml (20 mg of iron) to children weighing more than 14 kg and half day dose (1.5 mg / kg body weight) for children weighing less than 14 kg.
If no side reactions occur within 15 minutes after drug administration, the remaining amount of the initial dose is administered.
Prescription to children under 4 months is contraindicated because of the lack of experience of use.
The dose for each patient is calculated individually depending on the degree of iron deficiency according to the following formula:
Total iron deficiency (mg) = Body weight (kg) x (normal hemoglobin level - actual hemoglobin level) (g / l) x 0.24 * + iron stocks (mg)
where, * Coefficient 0.24 = 0.0034 x 0.07 x 1 000 (iron content in hemoglobin ~ 0.34% / Blood volume ~ 7% of body weight / Coefficient 1 000 = recalculation from g to mg).
For patients with a body weight of less than 34 kg: normal hemoglobin level = 130 g / l; iron stores = 15 mg / kg body weight.
For patients with a body weight of more than 34 kg: normal hemoglobin level = 150 g / l; iron stocks = 500 mg / kg body weight.
Total number of Fer-Rhompharm ampoules per treatment course (mg) = Total iron deficiency / 100 mg.
Total number of ampoules (ml) of Fer-Rhompharm 50 mg / ml for the course of treatment:
| Body weight (kg) | Hb 60 (g / l) | Hb 75 (g / l) | Hb 90 (g / l) | Hb 105 (g / l) |
| 5 | 1.5 (3 ml) | 1.5 (3 ml) | 1.5 (3 ml) | 1 (2 ml) |
| 10 | 3 (6 ml) | 3 (6 ml) | 2.5 (5 ml) | 2 (4 ml) |
| 15 | 5 (10 ml) | 4.5 (9 ml) | 3.5 (7 mL) | 3 (6 ml) |
| 20 | 6.5 (13 ml) | 5.5 (11 mL) | 5 (10 ml) | 4 (8 ml) |
| 25 | 8 (16 ml) | 7 (14 ml) | 6 (12 ml) | 5.5 (11 mL) |
| 30 | 9.5 (19 ml) | 8.5 (17 ml) | 7.5 (15 mL) | 6.5 (13 ml) |
| 35 | 12.5 (25 ml) | 11.5 (23 mL) | 10 (20 ml) | 9 (18 ml) |
| 40 | 13.5 (27 mL) | 12 (24 ml) | 11 (22 ml) | 9.5 (19 ml) |
| 45 | 15 (30 ml) | 13 (26 mL) | 11.5 (23 mL) | 10 (20 ml) |
| 50 | 16 (32 ml) | 14 (28 ml) | 12 (24 ml) | 10.5 (21 ml) |
| 55 | 17 (34 ml) | 15 (30 ml) | 13 (26 mL) | 11 (22 ml) |
| 60 | 18 (36 ml) | 16 (32 ml) | 13.5 (27 mL) | 11.5 (23 mL) |
| 65 | 19 (38 ml) | 16.5 (33 ml) | 14.5 (29 ml) | 12 (24 ml) |
| 70 | 20 (40 ml) | 17.5 (35 mL) | 15 (30 ml) | 12.5 (25 ml) |
| 75 | 21 (42 ml) | 18.5 (37 mL) | 16 (32 ml) | 13 (26 mL) |
| 80 | 22.5 (45 ml) | 19.5 (39 ml) | 16.5 (33 ml) | 13.5 (27 mL) |
| 85 | 23.5 (47 mL) | 20.5 (41 ml) | 17 (34 ml) | 14 (28 ml) |
| 90 | 24.5 (49 mL) | 21.5 (43 ml) | 18 (36 ml) | 14.5 (29 ml) |
If the total dose exceeds the maximum daily dose, it is necessary to divide the administration of the drug into several doses. If after 1-2 weeks of therapy there is no response from hematological parameters (for example, an increase in the hemoglobin concentration by about 1 g / L per day), the diagnosis should be reviewed.
Standard dosage:
Adults and elderly patients: 1-2 ampules of Fer-Rhompharm (100-200 mg of iron) 2 or 3 times a week, depending on the level of hemoglobin.
Children (of any age): 0.06 ml of Fer-Rhompharm / kg of body weight / day = 3 mg of iron / kg of body weight / day 2 or 3 times a week, depending on the level of hemoglobin.
The maximum daily dose:
Children with body weight up to 5 kg: 0.5 ml (1/4 ampoules = 25 mg of iron).
Children with a body weight of 5-10 kg: 1 ml (1/2 ampoules = 50 mg of iron).
Patients with a body weight of 10-45 kg: 2 ml (1 ampoule = 100 mg of iron).
Adults and elderly patients: 4 ml (2 ampoules = 200 mg of iron).
Technique of intramuscular injection
a) Needle length must be at least 5-6 cm. The needle clearance should not be too wide. For children, as well as for adults with a small body weight, needles should be shorter and thinner;
b) the injection site is defined as follows (see Figure 1): along the line of the spinal column at the level corresponding to the lumbosacral articulation, fix the point A. If the patient lies on the right side, place the middle finger of the left arm at point A. Set the index finger from the middle so that it is under the iliac crest line at point B. The triangle, located between the proximal phalanges of the middle and index fingers, is the injection site (see Figure 2);
c) tools are disinfected using the usual method; before inserting the needle, it is necessary to move the skin about 2 cm (see Figure 3) in order to close the puncture hole well after removing the needle. This prevents penetration of the injected solution into the subcutaneous tissues and staining the skin;
d) position the needle vertically with respect to the skin surface, at a greater angle to the point of the iliac joint than to the point of the femoral joint (see Figure 4);
e) after the injection, slowly take out the needle and press the finger of the skin area adjacent to the injection site for approximately 1 minute;
e) after the injection, the patient needs to move.