Fljuditik - instructions for use, dose, side effects, contraindications

Excipients: glycerol 5.0 g, methyl parahydroxybenzoate 0.15 g, sucrose 35.0 g, dye sunset yellow (E 110) 0.0016 g, dye patented blue V (E131) 0.001 g, sodium hydroxide to pH 6.2, aroma caramel 0.2 g, water purified to 100 ml.

Description:

Transparent liquid of green color with a caramel smell.

Pharmacotherapeutic group:mucolytic agent

ATX: & nbsp

R.05.C.B.03 Carbocysteine

Pharmacodynamics:Mucolytic and expectorant action is due to the activation of sialic transferase enzyme goblet cells of the bronchial mucosa.Normalizes the quantitative ratio of acidic and neutral sialomucines of bronchial secretion, restores the viscosity and elasticity of mucus, facilitates its departure. Promotes regeneration of the mucous membrane, normalizes its structure, reduces the production of mucus, activates the activity of the ciliary epithelium, improves mucociliary clearance. Restores the secretion of immunologically active IgA (specific protection) and the amount of sulfhydryl groups of mucus components (nonspecific protection).

Pharmacokinetics:

The maximum concentration in the blood serum and in the mucous membrane of the respiratory tract is achieved 2-3 hours after ingestion and remains in the mucous membrane for 8 hours. It is excreted mainly by the kidneys, partly unchanged, partly in the form of metabolites.

Indications:

Acute and chronic bronchopulmonary diseases (tracheitis, bronchitis, tracheobronchitis, bronchial asthma, bronchiectatic disease) and inflammatory diseases of the nasal cavity, nasopharynx, paranasal sinuses and middle ear (rhinitis, adenoiditis, sinusitis, otitis media) accompanied by the formation of a viscous, hardly secretable secretion (sputum, mucus); preparation for bronchoscopy and / or bronchography.

Contraindications:

- Pincreased sensitivity to carbocysteine or other components of the drug;

- peptic ulcer of the stomach and duodenum in the stage of exacerbation;

- chronic glomerulonephritis (in the phase of exacerbation), cystitis;

- children's age till 15 years;

- pregnancy (I trimester).

Carefully:

Care should be taken when taking the drug with chronic glomerulonephritis (in the anamnesis), peptic ulcer of the stomach and duodenum (in the anamnesis).

Pregnancy and lactation:

With caution appoint the drug during pregnancy (II and III trimesters) and breastfeeding.

Dosing and Administration:

For oral administration.

For 15 ml 3 times a day, preferably 1 hour before meals or 2 hours after eating.

Treatment should not last more than 8-10 days without consulting a doctor.

15 ml of syrup contains 750 mg of carbocysteine.

Side effects:

Nausea, vomiting, diarrhea, epigastric pain, flatulence, gastrointestinal bleeding, dizziness, weakness, malaise, in rare cases - allergic reactions (itching, urticaria, exanthema, angioedema).

If any of the side effects listed in the manual are aggravated,or you notice any other side effects not listed in the instructions, tell your doctor.

Overdose:

Symptoms: gastralgia, nausea, diarrhea.

Treatment: symptomatic.

Interaction:

When combined with glucocorticosteroids, a synergistic effect is observed. Increases the effectiveness of antibacterial therapy for inflammatory diseases of the upper and lower respiratory tract. Strengthens the bronchodilator effect of theophylline. Carbocisteine activity is weakened by antitussive and atropine-like agents.

Special instructions:

Only for adults.

Patients with diabetes should take into account that the content of sucrose per one tablespoon of syrup is 5.25 g.

Effect on the ability to drive transp. cf. and fur:

There is no evidence of a negative effect of the drug on the ability to drive vehicles and other mechanisms.

Form release / dosage:

A syrup of 50 mg / ml.

Packaging:For 125 ml of syrup in a clear glass bottle, closed with a plastic screw cap with a plastic gasket and with an opening control.

One bottle with a measuring cup of polypropylene and instructions for use in a cardboard bundle.

Storage conditions:

Store at a temperature not exceeding 25 ° C.

Keep out of the reach of children.

Shelf life:

2 years.

He apply at the expiration date indicated on the package.

Terms of leave from pharmacies:Without recipe

Registration number:П N014782 / 01-2003

Date of registration:09.02.2009

The owner of the registration certificate:Laboratory Innotech InternationalLaboratory Innotech International France

Manufacturer: & nbsp

INNOTHERA CHOUZY France

Representation: & nbspLaboratory Innotech International Laboratory Innotech International France

Information update date: & nbsp27.03.2012

Illustrated instructions

Instructions

Fluidite® (Fluditec®)