Fluviert - instructions for use, doses, side effects, contraindications

auxiliary components: sucrose 40.0 g, natural essence of cherry 0.25 g, methyl p-hydroxybenzoate 0.15 g, caramel 0.03 g, purified water up to 100 ml.

Description:

A clear solution of a dark yellow color with a characteristic smell of cherries.

Pharmacotherapeutic group:mucolytic agent

ATX: & nbsp

R.05.C.B.03 Carbocysteine

Pharmacodynamics:

Mucolytic and expectorant action is due to the activation of sialic transferase - the enzyme of goblet cells of bronchial mucosa.

Normalizes the quantitative ratio of acidic and neutral sialomucines of bronchial secretion, restores the viscosity and elasticity of mucus.Promotes regeneration of the mucous membrane, normalizes its structure, activates the activity of the ciliary epithelium. Restores the secretion of immunologically active IgA (specific protection) and the amount of sulfhydryl groups of mucus components (nonspecific protection), improves mucociliary clearance.

Pharmacokinetics:

Quickly and completely absorbed after oral administration. The maximum concentration in the blood and secretion is reached within the first hour after taking the drug. The therapeutic concentration is stored in the blood for 8 hours. T1 / 2 - 1.8 hours.

It is excreted mainly in the urine, about 30-60% - unchanged, the rest - in the form of metabolites.

Indications:

Acute and chronic bronchopulmonary diseases, accompanied by the formation of viscous and difficult to separate sputum (tracheitis, bronchitis, tracheobronchitis, bronchial asthma, bronchiectatic disease) and mucus (inflammatory diseases of the middle ear and paranasal sinuses - rhinitis, adenoiditis, otitis media, sinusitis), patient preparation bronchoscopy or bronchography.

Contraindications:

Hypersensitivity to carbocysteine,peptic ulcer of the duodenum and stomach (in the phase of exacerbation). Children under 1 year old, pregnancy (I trimester), lactation.

Carefully:Pregnancy II-III trimester, peptic ulcer and 12 duodenal ulcer (in the anamnesis).

Pregnancy and lactation:

It is not recommended to use the drug in the first trimester of pregnancy and during lactation.

Dosing and Administration:

Inside. A measuring cup with divisions is attached to the package, according to recommended doses.

Children older than 5 years: 5 ml of syrup (450 mg) - 2-3 times a day.

Children from 1 to 5 years: 2.5 ml of syrup (225 mg) - 2-3 times a day.

Adults: 15 ml of syrup (1.35 g) - 2-3 times a day.

The duration of treatment is determined by the doctor (from 4 days to 6 months).

This dosage is maintained for patients with impaired liver and kidney function, as well as for patients with diabetes.

To open the bottle, push firmly on top of the cap and turn it counter-clockwise. After application, tighten the cap again tightly.

Side effects:

For carbocisteine, the following side effects are typical: rarely - gastritis, nausea, diarrhea, dizziness, malaise, skin rash.

Lysine salt of carbocysteine: rarely - epigastric pain, nausea, diarrhea; skin rash.

All these disorders are transient and disappear after discontinuation of the drug or after a reduction in dosage.

If any side effect occurs, you should consult your doctor.

Overdose:At present, no cases of an overdose with Fluifert have been reported. Possible symptoms of an overdose: stomach pain, nausea, diarrhea. Treatment: symptomatic. There is no specific antitode.

Interaction:

At present, there are no known cases of interaction of carbocisteine and drugs commonly used in the treatment of respiratory diseases. There was no interaction of the drug and food products, as well as substances used for laboratory research.

The effect is weakened by antitussive and M-anticholinergic drugs. Increases the effectiveness of glucocorticosteroids (mutually) and antibacterial therapy of infectious and inflammatory diseases of the upper and lower respiratory tract. Strengthens the bronchodilator effect of theophylline.

Special instructions:

Since the first days of taking the drug, due to improved secretion, the expectorant effect is enhanced.

Fluviert syrup contains sucrose. This should be taken into account by patients adhering to the hypocaloric diet and patients with diabetes mellitus. With concomitant diabetes it is necessary to take into account the content of sucrose in syrup: 5.25 g per 1 tablespoon in syrup for adults and 3.5 g for 1 teaspoon in syrup for children. Treatment can be combined with physiotherapy procedures.

The use of Fluviert does not lead to the emergence of addiction or metabolic dependence.

Form release / dosage:Syrup, 100 ml.

Packaging:

For 100 ml of syrup in a bottle of dark glass.

The bottle is closed with a plastic lid, protected from opening by children.

1 bottle complete with a measuring cup of polypropylene and instructions for use in a pack of cardboard.

Storage conditions:

Store at a temperature not exceeding 25 ° C, in a place inaccessible to children.

Shelf life:

2 years.

Do not use after the date shown on the package.

Terms of leave from pharmacies:Without recipe

Registration number:П N010489 / 01

Date of registration:21.06.2010

The owner of the registration certificate:Dompe Pharmacetici SpA Dompe Pharmacetici SpA Italy

Manufacturer: & nbsp

DOMPE, S.p.A. Italy

Representation: & nbspCBS CJSC LTDCBS CJSC LTDItaly

Information update date: & nbsp13.05.2014

Illustrated instructions

Instructions

Fluviert (Fluifort)