Fluviert - instructions for use, doses, side effects, contraindications

auxiliary components: citric acid 0.080 g, mannitol 0.9185 g, povidone 0.1 g, natural cedar flavor 0.04 g, natural orange flavoring 0.04 g, orange juice powder 0.2960 g, aspartame 0.03 g, maltodextrine 0 , 7955

Description:

The granules are white to light yellow in color. The reconstituted solution is matte light yellow with the smell of citrus.

Pharmacotherapeutic group:mucolytic agent

ATX: & nbsp

R.05.C.B.03 Carbocysteine

Pharmacodynamics:

Mucolytic and expectorant action is due to the activation of sialic transferase - the enzyme of goblet cells of bronchial mucosa. Normalizes the quantitative ratio of acidic and neutral sialomucines of bronchial secretion, restores the viscosity and elasticity of mucus. Promotes regeneration of the mucous membrane, normalizes its structure, activates the activity of the ciliary epithelium. Restores the secretion of immunologically active IgA (specific protection) and the amount of sulfhydryl groups of mucus components (nonspecific protection), improves mucociliary clearance.

Pharmacokinetics:

Quickly and completely absorbed after oral administration. The maximum concentration in the blood and secretion is reached within the first hour after taking the drug. The therapeutic concentration is stored in the blood for 8 hours. T1 / 2 - 1.8 hours (at a dosage of 2 g / day).

It is excreted mainly in the urine, about 30-60% - unchanged, the rest - in the form of metabolites.

Indications:Acute and chronic bronchopulmonary diseases, accompanied by the formation of viscous and difficult to separate sputum (tracheitis, bronchitis, tracheobronchitis,bronchial asthma, bronchiectatic disease) and mucus (inflammatory diseases of the middle ear and paranasal sinuses - rhinitis, adenoiditis, otitis media, sinusitis), preparation of the patient for bronchoscopy or bronchography.

Contraindications:

Hypersensitivity to carbocysteine, peptic ulcer of the duodenum and stomach (in the phase of exacerbation). Children under 16 years of age, pregnancy (I trimester), lactation period, phenylketonuria.

Carefully:

Pregnancy (II-III trimester), peptic ulcer of the stomach and duodenum (in the anamnesis).

Pregnancy and lactation:

It is not recommended to use the drug in the first trimester of pregnancy and during lactation.

Dosing and Administration:

Inside.

Adults: 1 packet per day.

Dissolve the contents of the sachet in drinking water, mix.

The duration of treatment is determined by the doctor (from 4 days to 6 months).

This dosage is maintained for patients with impaired liver and kidney function, as well as for patients with diabetes.

Side effects:

For carbocisteine, the following side effects are typical: rarely - gastritis, nausea, diarrhea, dizziness, malaise, skin rash.

Lysine salt of carbocysteine: rarely - epigastric pain, nausea, diarrhea; skin rash.

All these disorders are transient and disappear after discontinuation of the drug or after a reduction in dosage.

If any side effect occurs, you should consult your doctor.

Overdose:

At present, no cases of an overdose with Fluifert have been reported. Possible symptoms of an overdose: stomach pain, nausea, diarrhea.

Treatment: symptomatic. There is no specific antitode.

Interaction:

At present, there are no known cases of interaction of carbocisteine and drugs commonly used in the treatment of respiratory diseases. There was no interaction between the drug and food products, as well as substances used for laboratory testing. The effect is weakened by antitussive drugs and M-anticholinergic drugs. Increases the effectiveness of glucocorticosteroids (mutually) and antibacterial therapy of infectious and inflammatory diseases of the upper and lower respiratory tract. Strengthens the bronchodilator effect of theophylline.

Special instructions:

Since the first days of taking the drug, due to improved secretion, the expectorant effect is increasing.

Fluid in the form of a granulated mixture for oral administration contains a sweetening agent aspartame. This substance is contraindicated in patients suffering from phenylketonuria.

The use of Fluviert does not lead to the emergence of addiction or metabolic dependence.

Treatment can be combined with physiotherapy procedures.

Form release / dosage:

For 5 g of the drug in a bag.

Packaging:10 bags of 2.7 g / 5 g in a cardboard pack with instructions for use.

Storage conditions:

Store at a temperature not higher than 25 ° C, out of the reach of children.

Shelf life:

Fluviert granulate - 3 years

Do not use after the date shown on the package.

Terms of leave from pharmacies:Without recipe

Registration number:П N010489 / 02

Date of registration:10.06.2010

The owner of the registration certificate:Dompe Pharmacetici SpA Dompe Pharmacetici SpA Italy

Manufacturer: & nbsp

DOMPE, S.p.A. Italy

Representation: & nbspCBS CJSC LTDCBS CJSC LTDItaly

Information update date: & nbsp16.05.2011

Illustrated instructions

Instructions

Fluviert (Fluifort)