Phosphogliv® forte (Phosphogliv® forte)

Composition Pharmacodynamics Indications Carefully Contraindications Dosing and Administration Side effects Form release / dosage
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Active substanceGlycyrrhizic acid + PhospholipidsGlycyrrhizic acid + Phospholipids
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  • Phosphogliv®
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    PHARMSTANDART-UFIM VITAMIN FACTORY, OJSC     Russia
  • Phosphogliv®
    capsules inwards 
    PHARMSTANDART-FORESTRY, OJSC     Russia
  • Phosphogliv® forte
    capsules inwards 
    PHARMSTANDART-FORESTRY, OJSC     Russia
  • Essenciglive
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    MINSKINTERKAPS, UP     Republic of Belarus
    • Dosage form: & nbspcapsules
    Composition:

    Composition per one capsule:

    Phospholipids (Lipoid PPL-400) 400.0 mg [in terms of 100% substance (main component - phosphatidylcholine 73-79%)] 300.0 mg, sodium glycyrrhizinate (trisodium salt glycyrrhizic acid) 65.0 mg;

    Excipients: Butylhydroxytoluene 0.1 mg, ethyl alcohol "luxury" or "extra" (ethanol) 12 mg, sunflower oil or corn oil 22.9 mg.

    Capsule shell composition:

    Hard gelatin capsules № 0

    Body and cover: titanium dioxide, iron oxide red oxide, iron oxide black oxide, iron oxide oxide yellow, gelatin.

    Description:

    Capsules hard gelatinous №0; The body and cap of the capsule are brown.

    The contents of the capsule are an oily paste-like mass from light yellow to orange-brown in color with a weak specific odor.

    Pharmacotherapeutic group:hepatoprotective agent
    ATX: & nbsp

    A.05.B.A   Preparations for the treatment of liver diseases

    Pharmacodynamics:

    Combined means. Has a membrane-stabilizing, hepatoprotective and antiviral effect.

    Phosphatidylcholine (the main component of phospholipids) is the main structural element of cellular and intracellular membranes, capable of restoring their structure and functions in damage, providing a cytoprotective effect.

    Normalizes protein and lipid metabolism, prevents the loss of hepatocytes enzymes and other active substances, restores the detoxification function of the liver, inhibits the formation of connective tissue, reducing the risk of fibrosis and cirrhosis.

    Glycyrate (glycyrrhizic acid and salts) has an anti-inflammatory effect, suppresses the reproduction of viruses in the liver and other organs by stimulating the production of interferons, increasing phagocytosis, increasing the activity of natural killer cells. Has a hepatoprotective effect due to antioxidant and membrane-stabilizing activity.Potentiates the effect of endogenous glucocorticosteroids, providing anti-inflammatory and anti-allergic effects in non-infectious liver lesions.

    When the skin is damaged due to the membrane-stabilizing and anti-inflammatory effect of the components, it limits the spread of the process and promotes regression of the disease.

    Pharmacokinetics:

    The components of the preparation are well absorbed in the intestine both in the form of the whole molecule and the bioactive products of their hydrolysis (unsaturated fatty acids, choline, glycyrrheic acid), which after absorption through the intestinal walls easily penetrate into the liver, lungs, skin and other organs.

    Indications:

    Viral hepatitis (acute and chronic), fatty liver degeneration (hepatosis), other liver damage (medicinal, alcoholic, toxic), liver cirrhosis, intoxications, psoriasis, neurodermatitis, eczema.

    Contraindications:

    Hypersensitivity to the components of the drug, pregnancy, lactation, children under 12 years.

    Dosing and Administration:

    Is taken orally, with food, with a small amount of liquid.

    Adults 1-2 capsules 3 times a day, children over 12 years - 1 capsule 3 times a day.
    Side effects:

    With increased individual sensitivity, skin rashes may appear, which disappears after the drug is discontinued.

    Rarely, if daily doses are exceeded, sodium and liquid retention may occur, which is manifested by peripheral edema and increased blood pressure, hypokalemia. When these symptoms appear, depending on their severity, it is necessary to reduce the dose of the drug and / or to prescribe spironolactone 50-100 mg per day.
    Overdose:Not checked.
    Interaction:

    Not described.

    Form release / dosage:

    Capsules, 300 mg + 65 mg.

    Packaging:

    For 30, 50, 100, 200 or 300 capsules in plastic containers with high-pressure polyethylene or propylene lids or polymer cans, sealed with tamper-evident covers with a moisture-absorbing insert.

    10 capsules per contour cell packaging made of polyvinylchloride film and aluminum foil.

    1 container or 2, 3, 5 contour mesh packages together with instructions for use are placed in a pack of cardboard.

    Storage conditions:

    Store at a temperature not exceeding 25 ° C.

    Keep out of the reach of children.

    Shelf life:

    3 years.

    At the end of the expiration date the drug should not be used.

    Terms of leave from pharmacies:On prescription
    Registration number:LSR-008120/08
    Date of registration:14.10.2008
    The owner of the registration certificate:PHARMSTANDART-FORESTRY, OJSC PHARMSTANDART-FORESTRY, OJSC Russia
    Manufacturer: & nbsp
    Information update date: & nbsp22.12.2015
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